Colorectal Cancer
Copyright ©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 15, 2004; 10(8): 1167-1170
Published online Apr 15, 2004. doi: 10.3748/wjg.v10.i8.1167
Laparoscopic versus conventional open resection of rectal carcinoma: A clinical comparative study
Wen-Xi Wu, Yao-Min Sun, Yi-Bin Hua, Li-Zong Shen
Wen-Xi Wu, Yao-Min Sun, Yi-Bin Hua, Li-Zong Shen, Department of Gastrointestinal Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Author contributions: All authors contributed equally to the work.
Supported by Jiangsu Province Educational Foundation
Correspondence to: Dr. Wen-Xi Wu, Department of Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanijng 210029, Jiangsu Province, China. wuwenxi@yahoo.com
Telephone: +86-25-3718836-6863 Fax: +86-25-6863798
Received: June 5, 2003
Revised: August 1, 2003
Accepted: August 25, 2003
Published online: April 15, 2004
Abstract

AIM: To evaluate the feasibility of laparoscopic resection of rectal carcinoma and to compare the short-term outcome of laparoscopic procedure with conventional open surgery for rectal cancer.

METHODS: Thirty-eight patients with rectal cancer were included in a prospective non-randomized study. The patients were assigned to laparoscopic (n = 18) or open (n = 18) colorectal resection. Case selection, surgical technique, and clinical and pathological results were reviewed.

RESULTS: The operative time was longer in laparoscopic resection group (LAP) than in open resection group (189 ± 18 min vs 146 ± 22 min, P < 0.05). Intraoperative blood loss and postoperative complications were less in LAP resection group than in open resection group. An earlier return of bowel motility was observed after laparoscopic surgery. The overall postoperative morbidity was 5.6% in the LAP resection group and 27.8% in open resection group (P < 0.05). No anastomotic leakage was found in both groups. The pathologic examination showed that the length of the resected specimen, the mean number of harvested lymph nodes in laparoscopic resection group were comparable to those in open resection group.

CONCLUSION: Laparoscopic total mesorectal excision (TME) for rectal cancer is a feasible but technically demanding procedure. The present study demonstrates the safety of the procedure, while oncologic results are comparable to the open surgery, with a favorable short-term outcome.

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