Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT

doi:10.3748/wjg.v10.i18.2753

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 15, 2004; 10(18): 2753-2755
Published online Sep 15, 2004. doi: 10.3748/wjg.v10.i18.2753

Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT

Hong-Yan Cheng, Yi Shou, Xiang Wang, Ai-Min Xu, Dong Chen, Yu-Chen Jia

Hong-Yan Cheng, Yi Shou, Xiang Wang, Ai-Min Xu, Dong Chen, Yu-Chen Jia, Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. Hong-Yan Cheng, Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China

Telephone: +86-21-25070861 Fax: +86-21-25070861

Received: December 28, 2003
Revised: January 5, 2004
Accepted: January 12, 2004
Published online: September 15, 2004

Abstract

AIM: To work out an individualized lipiodol dose in transcatheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT.

METHODS: One hundred patients with large HCC (more than 8 cm in diameter) were studied by multidetector helical CT. Patterns of blood supply of HCC were divided into sufficient blood supply, poor blood supply, mixed blood supply and arteriovenous (A-V) shunt. The dose of ultra-fluid lipiodol was determined by diameter and blood supply type of HCC. Patients were divided into two groups (50 cases each): lipiodol perfusion group and iodized oil perfusion group according to tumor diameter and the blood supply type of tumor.

RESULTS: The confirmation and effective rates were 82%, 84% in the first group and 36%, 46% in the second group (P < 0.01).

CONCLUSION: A relatively individualized lipiodol dose may be determined according to the blood supply pattern and the tumor diameter by CT imaging.

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