Effect of parenteral and enteral nutrition combined with octreotide on pancreatic exocrine secretion of patients with pancreatic fistula

doi:10.3748/wjg.v10.i16.2419

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 10, Issue 16

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3121)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-2) series.

Item

Count

PDF

287

HTML

2392

Figures (1-1)

213

Tables (1-2)

229

Sum=3121

Aug 15, 2004 (publication date) through Dec 21, 2024

Times Cited of This Article

Times Cited (14)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Brief Reports

World J Gastroenterol. Aug 15, 2004; 10(16): 2419-2422
Published online Aug 15, 2004. doi: 10.3748/wjg.v10.i16.2419

Effect of parenteral and enteral nutrition combined with octreotide on pancreatic exocrine secretion of patients with pancreatic fistula

Huan-Long Qin, Zhen-Dong Su, Yang Zou, You-Ben Fan

Huan-Long Qin, Zhen-Dong Su, Yang Zou, You-Ben Fan, Department of Surgery, Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai 200233, China

Author contributions: All authors contributed equally to the work.

Supported by the Shanghai Science Foundation for Distinguished Young Scholars, No.99QB14010

Correspondence to: Huan-Long Qin, Department of Surgery, Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai 200233, China. jiaqc@online.sh.cn

Telephone: +86-21-64368920 Fax: +86-21-64368920

Received: December 10, 2003
Revised: December 22, 2004
Accepted: January 15, 2004
Published online: August 15, 2004

Abstract

AIM: To evaluate the effect of parenteral and enteral nutrition combined with octreotide on pancreatic exocrine secretion of the patients with pancreatic fistula.

METHODS: Pancreatic juice, drained directly from the pancreatic fistula, was collected, and the volume, protein, amylase, HCO₃^-, K⁺, Na⁺ and Cl^- were determined on d 1, 4 and 7 before and after 7-d treatment with octreotide, respectively.

RESULTS: No differences in exocrine pancreatic secretion were observed during the enteral and parenteral nutrition period (t = 2.03, P > 0.05); there were significant decreases in pancreatic juice secretion volume, protein, amylase, HCO₃^-, K⁺, Na⁺ and Cl^- after parenteral and enteral nutrition combined with octreotide compared with octreotide pretreatment (t = 4.14, P < 0.05).

CONCLUSION: There is no stimulatory effect on the pancreatic secretion by intrajejunal nutrition and parenteral nutrition. Octreotide is effective on the reduction of pancreatic fistula output.

Keywords: $[Keywords]