Clinical Research
Copyright ©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 15, 2004; 10(12): 1795-1797
Published online Jun 15, 2004. doi: 10.3748/wjg.v10.i12.1795
Investigation of regurgitation and other symptoms of gastroesophageal reflux in Indonesian infants
Badriul Hegar, Aswitha Boediarso, Agus Firmansyah, Yvan Vandenplas
Badriul Hegar, Aswitha Boediarso, Agus Firmansyah, Department of Pediatrics, Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia
Yvan Vandenplas, Department of Pediatrics, Academisch Ziekenhuis Vrije UniversiteitBrussel, Brussels, Belgium
Author contributions: All authors contributed equally to the work.
Correspondence to: Yvan Vandenplas, Department of Pediatrics, Academic Children’s Hospital, VUB, Laarbeeklaan 101, 1090 Brussels, Belgium. yvan.vandenplas@az.vub.ac.be
Telephone: +32-24775780 Fax: +32-24775783
Received: September 9, 2003
Revised: November 23, 2003
Accepted: December 1, 2003
Published online: June 15, 2004
Abstract

AIM: To evaluate the incidence of regurgitation and other symptoms of gastroesophageal reflux in Indonesian infants.

METHODS: In a cross-sectional study at the University Outpatient Clinic for vaccination in Jakarta, 138 mothers of healthy infants less than 12-mo old were prospectively asked to report the frequency of regurgitation.

RESULTS: Whatever the age was, some infants did not regurgitate (from 10% during the first month of life to 67% in 1-year-old infants). Regurgitation of at least once a day was reported in 77% of infants younger than 3 mo. Daily regurgitation decreased to 12% in the 9-12 mo old group. Reported peak prevalence was 81% (26/32) during the first month of life. Regurgitation decreased sharply between the 4-6 and 7-9 mo old groups (from 44% to 9%). The longer the regurgitation persisted, the more frequently the mother perceived regurgitation as a problem. Volume and frequency of regurgitation, back arching, irritability, crying and refusal of feeding were the symptoms causing maternal anxiety. The longer the regurgitation persisted, the more frequently the mothers viewed it as a health problem.

CONCLUSION: Regurgitation occurs frequently in Indonesian infants, and is a frequent cause of concern to mothers.

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