• abdominal pain
• acute appendicitis
• angiolipoma
• case report
• laparoscopy
• lipoma

Angiolipomas are benign mesenchymal tumors that often occur under the skin of the upper extremity or thoracic and abdominal walls. Angiolipomas of the digestive tract are rare. Here, we describe a case of transverse colon angiolipoma with intussusception resected by laparoscopy-assisted surgery. A 50-year-old woman visited a family hospital with complaints of left lower abdominal pain and bloody stool. Colonoscopy revealed a submucosal tumor in her left colon. She was referred to our hospital for further examination. Computed tomography revealed a low-density tumor with intussusception in the left transverse colon. Elective surgery was planned for this patient because there were no alarming symptoms such as ileus or obstruction. Laparoscopy-assisted surgery and partial resection of the left transverse colon were performed. The histopathological diagnosis was angiolipoma of the colon. Angiolipomas are benign mesenchymal tumors that rarely occur in the digestive tract. Thus, accurate preoperative diagnosis is difficult.

Angiolipoma is a benign tumor that rarely occurs in the gastrointestinal (GI) tract. This case series was performed to increase clinicians’ understanding of the diagnosis and management of GI angiolipoma.

We evaluated the clinical presentations, diagnoses, and treatments of 3 patients with angiolipoma in the upper GI tract in our hospital and 27 cases reported in the literature.

Among all 30 cases of GI angiolipoma, 2 originated in the esophagus, 4 in the stomach, 2 in the duodenum, 1 in the jejunum, 7 in the ileum, 1 in the cecum, 9 in the colon, 2 in the rectum, and 2 in both the duodenum and colon.

Angiolipoma of the GI tract may be more likely to occur in middle-aged and elderly men and be located in the ileum and colon. The clinical manifestations generally involve upper GI hemorrhage and lower GI pain and obstruction. Computed tomography and endoscopy may be effective diagnostic techniques, but postoperative histopathologic examination is still the gold standard. The management of angiolipoma in the GI tract depends on the size and type of lesion. Most cases in the present series were managed by complete surgical resection, after which no recurrence was found.

• Angiolipoma
• benign tumor
• case series
• complete resection
• gastrointestinal tract
• histopathology

• Aged
• Angiolipoma/diagnostic imaging
• Angiolipoma/surgery
• Endoscopy
• Gastrointestinal Hemorrhage/diagnostic imaging
• Gastrointestinal Tract
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local

• Beijing Municipal Science and Technology Commission
• Chinese Society of Clinical Oncology

Angiolipoma is a morphological variation of the lipoma and is a benign tumour that consists of mature adipose tissue and proliferating blood vessels. It occurs very rarely in the digestive tract, especially the stomach. We report a gastric angiolipoma in a 58-year-old woman admitted for anaemia and melena. Endoscopy showed a large polypoid mass with superficial ulceration in the anterior wall of the gastric antrum. Endoscopic ultrasound showed an about 2 cm sized isoechoic lesion at the third echo layer, with the echogenic portion on the luminal side of the lesion. Laparoscopic wedge resection was performed and histological examination showed that the lesion had encapsulated adipose tissue at the submucosal layer and stromal fibrosis just below superficial ulceration. There were blood vessels with thick walls among the mature fat cells. Therefore, the lesion was diagnosed as an angiolipoma.

• anaemia
• angiolipoma
• stomach

• gastrointestinal tract angiolipoma
• colon angiolipoma
• intussusception
• colon cancer

• Angiolipoma/complications
• Angiolipoma/pathology
• Angiolipoma/surgery
• Colonic Neoplasms/complications
• Colonic Neoplasms/pathology
• Colonic Neoplasms/surgery
• Colonoscopy
• Gastrointestinal Hemorrhage/etiology
• Gastrointestinal Hemorrhage/pathology
• Gastrointestinal Hemorrhage/surgery
• Humans
• Intussusception/etiology
• Intussusception/pathology
• Intussusception/surgery
• Male
• Middle Aged
• Prognosis
• Review Literature as Topic

• Angiolipoma
• Colon
• Computed tomography

• Aged
• Angiolipoma/diagnosis
• Colonic Neoplasms/diagnosis
• Colonoscopy
• Diagnosis, Differential
• Humans
• Male
• Rare Diseases/diagnosis
• Tomography, X-Ray Computed

Angiolipomas are frequently observed benign tumours. They have a typical vascular component and are often located in subcutaneous tissues, and more rarely, in the gastrointestinal tract.

We report an uncommon case of an angiolipoma found in the lower portion of the small bowel of an 80-year-old man who was undergoing evaluation for chronic anaemia. A standardised diagnostic pathway was followed. Endoscopic and radiological findings were negative. The diagnosis was finally established with the aid of capsule endoscopy. The case we report is the first in the literature of an angiolipoma without specific painful symptoms. In fact, the patient did not complain of abdominal pain or alvus changes, and abdominal examination did not suggest an expansive process. The endoscopic study performed with the capsule identified the lesion as the cause of the ingravescent anaemia. Intra-operative histological examination of the lesion made it possible to avoid a major surgical procedure and assured a short postoperative course for the patient.

This report focuses on the importance of correct pre- and/or intra-operative histological diagnosis in order to offer the best therapeutic choice. An angiolipoma was suspected in this case, even though they are rarely located in the ileum.

Angiolipoma is a rare vascular variant of the benign lipomatous tumors and is generally seen in subcutaneous tissues. We report a 70-year-old female with abdominal distension not related to rectal small polypoid mass with peduncule described as angiolipoma by histologically, and review the literature.

• Gastrointestinal tract angiolipoma
• Gastro-intestinal benign lipomatous tumors
• Rectal angiolipoma

• Aged
• Angiolipoma/diagnosis
• Angiolipoma/pathology
• Angiolipoma/surgery
• Colonoscopy
• Endoscopy, Gastrointestinal
• Female
• Humans
• Rectal Neoplasms/diagnosis
• Rectal Neoplasms/pathology
• Rectal Neoplasms/surgery

• Angiolipoma/pathology
• Cadaver
• Dissection
• Female
• Humans
• Middle Aged
• Umbilical Arteries/pathology

Angiolipoma is a common benign tumor with a characteristic vascular component that usually occurs in subcutaneous tissue. Although lipomas are frequently encountered at colonoscopy as submucosal tumors, angiolipomas are rarely found in the gastrointestinal tract including the large intestine. Here we report a 77-year old Japanese man who underwent transanal resection of a tumor that was diagnosed tentatively as a leiomyoma. Histologically, the tumor consisted of mature fat cells and blood vessels. Immunohistochemically, the tumor cells were negative for c-kit and HMB-45, which are consistently expressed in tumors such as gastrointestinal stromal tumor and angiomyolipoma. The tumor was therefore diagnosed as an angiolipoma. This is thought to be the first case report of a surgically resected angiolipoma of the rectum.

• Angiolipoma
• Angiomyolipoma
• Gastrointestinal stromal tumor

• Aged
• Angiolipoma/diagnosis
• Angiolipoma/surgery
• Humans
• Male
• Rectal Neoplasms/diagnosis
• Rectal Neoplasms/surgery

Angiolipoma, a common benign tumor mostly seen in the subcutaneous tissue, is a rare pathological condition in the gastrointestinal tract that is usually diagnosed postoperatively. In this case report, an angiolipoma was diagnosed preoperatively by imaging (including CT scans, abdominal echo, barium enema, and colonoscopy). This pathology was confirmed postoperatively. Computed tomography scan, abdominal echo, and barium enema images were presented.

• Angiolipoma
• Colon
• Computed tomography
• Sonography
• Contrast barium enema

• Aged
• Angiolipoma/diagnostic imaging
• Angiolipoma/surgery
• Barium
• Colonic Neoplasms/diagnostic imaging
• Colonic Neoplasms/surgery
• Colonoscopy
• Humans
• Male
• Preoperative Care
• Tomography, X-Ray Computed
• Ultrasonography

• Angiolipoma/pathology
• Angiolipoma/surgery
• Colonoscopy
• Electrosurgery
• Humans
• Male
• Middle Aged
• Sigmoid Neoplasms/pathology
• Sigmoid Neoplasms/surgery