• Adverse events
• BMI
• Complication
• Endoscopy
• Low body mass index

• cap-assisted colonoscopy
• difficult colonoscopy
• single-balloon-assisted colonoscopy

• Colon morphology
• Colonoscopy
• Human large intestine

• Adult
• Colonoscopy/instrumentation
• Female
• Humans
• Intra-Abdominal Fat
• Male

To identify the factors influencing cecal insertion time (CIT) and to evaluate the effect of obesity indices on CIT.

We retrospectively reviewed the data for participants who received both colonoscopy and abdominal computed tomography (CT) from February 2008 to May 2008 as part of a comprehensive health screening program. Age, gender, obesity indices [body mass index (BMI), waist-to-hip circumference ratio (WHR), waist circumference (WC), visceral adipose tissue (VAT) volume and subcutaneous adipose tissue (SAT) volume on abdominal CT], history of prior abdominal surgery, constipation, experience of the colonoscopist, quality of bowel preparation, diverticulosis and time required to reach the cecum were analyzed. CIT was categorized as longer than 10 min (prolonged CIT) and shorter than or equal to 10 min, and then the factors that required a CIT longer than 10 min were examined.

A total of 1678 participants were enrolled. The mean age was 50.42 ± 9.931 years and 60.3% were men. The mean BMI, WHR, WC, VAT volume and SAT volume were 23.92 ± 2.964 kg/m², 0.90 ± 0.076, 86.95 ± 8.030 cm, 905.29 ± 475.220 cm³ and 1707.72 ± 576.550 cm³, respectively. The number of patients who underwent abdominal surgery was 268 (16.0%). Colonoscopy was performed by an attending physician alone in 61.9% of cases and with the involvement of a fellow in 38.1% of cases. The median CIT was 7 min (range 2-56 min, IQR 5-10 min), and mean CIT was 8.58 ± 5.291 min. Being female, BMI, VAT volume and involvement of fellow were significantly associated with a prolonged CIT in univariable analysis. In multivariable analysis, being female (OR = 1.29, P = 0.047), lower BMI (< 23 kg/m²) (OR = 1.62, P = 0.004) or higher BMI (≥ 25 kg/m²) (OR = 1.80, P < 0.001), low VAT volume (< 500 cm³) (OR = 1.50, P = 0.013) and fellow involvement (OR = 1.73, P < 0.001) were significant predictors of prolonged CIT. In subgroup analyses for gender, lower BMI or higher BMI and fellow involvement were predictors for prolonged CIT in both genders. However, low VAT volume was associated with prolonged CIT in only women (OR = 1.54, P = 0.034).

Being female, having a lower or higher BMI than the normal range, a low VAT volume, and fellow involvement were predictors of a longer CIT.

• Visceral obesity
• Difficult colonoscopy
• Cecal insertion time
• Body mass index
• Female

• Adult
• Colonoscopy/statistics & numerical data
• Female
• Humans
• Intra-Abdominal Fat
• Male
• Middle Aged
• Obesity
• Retrospective Studies
• Time Factors

Many factors have been found to affect the difficulty of colonoscope insertion, such as age, gender, body mass index (BMI), history of abdominal surgery and operator etc. However, a scoring system may be more useful to predict the difficulty during colonoscopy.

The individual and procedure-related data of 616 patients undergoing colonoscopy were prospectively collected from December 2013 through February 2014 in Xijing Hospital of Digestive Diseases. Cox regression analysis was used to identify high-risk factors associated with difficulty of colonoscopy. A predicting model with the difficult colonoscopy score (DCS) was developed.

Total cecum intubation rate was 98.9% (609/616). Advanced age, lower BMI, inexperienced operator and fair or poor sleep quality were identified as independent factors of prolonged insertion time (all p < 0.05), which were used to develop the DCS. Based on the score, patients could be divided into high-risk and low-risk groups with distinct incomplete rates within 10 min (42.0% vs. 16.5%, p < 0.001). Compared with those with DCS ≤ 1, patients with DCS > 1 had increased insertion time (10.6 ± 0.7 min vs. 6.9 ± 0.2 min, p < 0.001) and pain score (1.9 ± 1.5 vs. 1.4 ± 1.4, p = 0.002). More abdominal compression (36.9% vs. 16.8%, p < 0.001) and position change (51.4% vs. 22.6%, p < 0.001) were needed in this group of patients.

Patients with DCS > 1 had longer insertion time, higher pain score and needed more abdominal compression and position changes. DCS was useful for predicting the difficulty of colonoscope intubation.

(ClinicalTrials.gov NCT02105025 05/05/2014).

The online version of this article (doi:10.1186/s12876-015-0273-7) contains supplementary material, which is available to authorized users.

• Colonoscope Length
• Colonoscopy
• Intubation Rate
• Intubation Time

• Adult
• Cecum
• Colonoscopes
• Colonoscopy/instrumentation
• Colonoscopy/methods
• Equipment Design
• Female
• Humans
• Ileum
• Intubation, Gastrointestinal/instrumentation
• Intubation, Gastrointestinal/methods
• Male
• Middle Aged
• Prospective Studies
• Surveys and Questionnaires
• Time Factors

• Adenocarcinoma/diagnosis
• Adenoma/diagnosis
• Adult
• Aged
• Aged, 80 and over
• Carcinoid Tumor/diagnosis
• Cecum
• Colonic Neoplasms/diagnosis
• Colonic Polyps/diagnosis
• Colonoscopy/instrumentation
• Colonoscopy/methods
• Equipment Design
• Female
• Gastroscopes
• Humans
• Male
• Middle Aged
• Prospective Studies
• Video Recording
• Young Adult

AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate.

METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study.

RESULTS: There were 200 cases in each group. There was no significant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no significant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists.

CONCLUSION: CAC did not significantly different from SC in term of cecal intubation time and polyp detection rate.

• Cap
• Hood
• Cecum
• Colonoscopy
• Cecal intubation
• Colonic polyps

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Colonic Neoplasms/diagnosis
• Colonoscopy
• Female
• Humans
• Male
• Middle Aged
• Obesity
• Preoperative Care
• Young Adult

• T32 DK007130 NIDDK NIH HHS
• T32 DK007301 NIDDK NIH HHS
• 5-T32-DK07301-35 NIDDK NIH HHS