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For: Liu JF, Zhou XK, Chen JH, Yi G, Chen HG, Ba MC, Lin SQ, Qi YC. Up-regulation of PIK3CA promotes metastasis in gastric carcinoma. World J Gastroenterol 2010; 16(39): 4986-4991 [PMID: 20954287 DOI: 10.3748/wjg.v16.i39.4986]
URL: https://www.wjgnet.com/1007-9327/full/v16/i39/4986.htm
Number Citing Articles
1
Xiaobing Shen, Ying Zhao, Xiaowei Chen, Haixiang Sun, Mengqi Liu, Wenwen Zhang, Fei Jiang, Pengfei Li. Associations of PIK3CA mutations with clinical features and prognosis in gastric cancerFuture Oncology 2019; 15(16): 1873 doi: 10.2217/fon-2018-0335
2
Christoph Treese, Kimberly Hartl, Michelle Pötzsch, Matthias Dahlmann, Moritz von Winterfeld, Erika Berg, Michael Hummel, Lena Timm, Beate Rau, Wolfgang Walther, Severin Daum, Dennis Kobelt, Ulrike Stein. S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and EsophagusCells 2022; 11(6): 1056 doi: 10.3390/cells11061056
3
Marianna Scrima, Carmela De Marco, Fernanda Fabiani, Renato Franco, Giuseppe Pirozzi, Gaetano Rocco, Maria Ravo, Alessandro Weisz, Pietro Zoppoli, Michele Ceccarelli, Gerardo Botti, Donatella Malanga, Giuseppe Viglietto, Alfredo Fusco. Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinasePLoS ONE 2012; 7(2): e30427 doi: 10.1371/journal.pone.0030427
4
Ismael Riquelme, Kathleen Saavedra, Jaime A. Espinoza, Helga Weber, Patricia García, Bruno Nervi, Marcelo Garrido, Alejandro H. Corvalán, Juan Carlos Roa, Carolina Bizama. Molecular classification of gastric cancer: Towards a pathway-driven targeted therapyOncotarget 2015; 6(28): 24750 doi: 10.18632/oncotarget.4990
5
Lin Wang, Ling Shan, Shaokai Zhang, Jianming Ying, Liyan Xue, Yanling Yuan, Yongqiang Xie, Ning Lu, Hiromu Suzuki. PIK3CA Gene Mutations and Overexpression: Implications for Prognostic Biomarker and Therapeutic Target in Chinese Esophageal Squamous Cell CarcinomaPLoS ONE 2014; 9(7): e103021 doi: 10.1371/journal.pone.0103021
6
Min Dong, Hai-yan Wang, Xiao-xiao Zhao, Jian-ning Chen, Yi-wang Zhang, Yan Huang, Ling Xue, Hai-gang Li, Hong Du, Xiang-yuan Wu, Chun-kui Shao. Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus–associated gastric carcinomaHuman Pathology 2016; 53: 25 doi: 10.1016/j.humpath.2016.02.007
7
B. Ye, L-L. Jiang, H-T. Xu, D-W. Zhou, Z-S. Li. Exression and PI3K/AKT Pathway in Gastric Cancer and its Blockade Suppresses Tumor Growth and MetastasisInternational Journal of Immunopathology and Pharmacology 2012; 25(3): 627 doi: 10.1177/039463201202500309
8
Yinbing Wu, Mingxin Pan, Shuzhong Cui, Mingchen Ba, Zulong Chen, Qiang Ruan. Autophagic death induced by thermo-chemotherapy in gastric cancer cells results from the reactive oxygen species pathwayMolecular Medicine Reports 2016; 14(2): 1210 doi: 10.3892/mmr.2016.5353
9
Si-Hyong Jang, Kyung-Ju Kim, Mee-Hye Oh, Ji-Hye Lee, Hyun Ju Lee, Hyun Deuk Cho, Sun Wook Han, Myoung Won Son, Moon Soo Lee. Clinicopathological Significance of Elevated PIK3CA Expression in Gastric CancerJournal of Gastric Cancer 2016; 16(2): 85 doi: 10.5230/jgc.2016.16.2.85
10
Ayda Baghery Saghchy Khorasani, Atieh Pourbagheri-Sigaroodi, Ali Pirsalehi, Ava Safaroghli-azar, Mohammad Reza Zali, Davood Bashash. The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventionsEuropean Journal of Pharmacology 2021; 898: 173983 doi: 10.1016/j.ejphar.2021.173983
11
T Matsuoka, M Yashiro, N Nishioka, K Hirakawa, K Olden, J D Roberts. PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinomaBritish Journal of Cancer 2012; 106(9): 1535 doi: 10.1038/bjc.2012.107
12
Zhengrong Li, Guoyang Zhang, Daojiang Li, Zhigang Jie, Heping Chen, Jianbo Xiong, Yi Liu, Yi Cao, Mengmeng Jiang, Zhibiao Le, Shengxing Tan. Methylation-associated silencing of miR-495 inhibit the migration and invasion of human gastric cancer cells by directly targeting PRL-3Biochemical and Biophysical Research Communications 2015; 456(1): 344 doi: 10.1016/j.bbrc.2014.11.083
13
Puja Khanna, Pei Jou Chua, Belinda Shu Ee Wong, Changhong Yin, Aye Aye Thike, Wei Keat Wan, Puay Hoon Tan, Gyeong Hun Baeg. GRAM domain-containing protein 1B (GRAMD1B), a novel component of the JAK/STAT signaling pathway, functions in gastric carcinogenesisOncotarget 2017; 8(70): 115370 doi: 10.18632/oncotarget.23265
14
Lara Alessandrini, Melissa Manchi, Valli De Re, Riccardo Dolcetti, Vincenzo Canzonieri. Proposed Molecular and miRNA Classification of Gastric CancerInternational Journal of Molecular Sciences 2018; 19(6): 1683 doi: 10.3390/ijms19061683
15
Maider Ibarrola-Villava, Marta J. Llorca-Cardeñosa, Noelia Tarazona, Cristina Mongort, Tania Fleitas, José Alejandro Perez-Fidalgo, Susana Roselló, Samuel Navarro, Gloria Ribas, Andrés Cervantes. Deregulation ofARID1A,CDH1,cMETandPIK3CAand target-related microRNA expression in gastric cancerOncotarget 2015; 6(29): 26935 doi: 10.18632/oncotarget.4775
16
Iacopo Panarese, Ferdinando De Vita, Andrea Ronchi, Marco Romano, Roberto Alfano, Natale Di Martino, Federica Zito Marino, Francesca Ferraraccio, Renato Franco. Predictive biomarkers along gastric cancer pathogenetic pathwaysExpert Review of Anticancer Therapy 2017; 17(5): 417 doi: 10.1080/14737140.2017.1301207
17
Carolina Martinez-Ciarpaglini, Tania Fleitas-Kanonnikoff, Valentina Gambardella, Marta Llorca, Cristina Mongort, Regina Mengual, Gema Nieto, Lara Navarro, Marisol Huerta, Susana Rosello, Desamparados Roda, Noelia Tarazona, Samuel Navarro, Gloria Ribas, Andrés Cervantes. Assessing molecular subtypes of gastric cancer: microsatellite unstable and Epstein-Barr virus subtypes. Methods for detection and clinical and pathological implicationsESMO Open 2019; 4(3): e000470 doi: 10.1136/esmoopen-2018-000470
18
Anastasija Ranceva, Rokas Stulpinas, Rimvydas Norvilas, Ugnius Mickys. Hepatoid adenocarcinoma of the stomach with PIK3Ca mutation during pregnancy: A case report with molecular profileOxford Medical Case Reports 2021; 2021(9) doi: 10.1093/omcr/omab078
19
Mohammad Rafi Khezri, Hsiang‐Yin Hsueh, Somayeh Mohammadipanah, Javad Khalili Fard, Morteza Ghasemnejad‐Berenji. The interplay between the PI3K/AKT pathway and circadian clock in physiologic and cancer‐related pathologic conditionsCell Proliferation 2024;  doi: 10.1111/cpr.13608
20
Carmela De Marco, Nicola Rinaldo, Paola Bruni, Carmine Malzoni, Fulvio Zullo, Fernanda Fabiani, Simona Losito, Marianna Scrima, Federica Zito Marino, Renato Franco, Alfina Quintiero, Valter Agosti, Giuseppe Viglietto, Xin-Yuan Guan. Multiple Genetic Alterations within the PI3K Pathway Are Responsible for AKT Activation in Patients with Ovarian CarcinomaPLoS ONE 2013; 8(2): e55362 doi: 10.1371/journal.pone.0055362
21
Anna Starzyńska, Paulina Adamska, Aleksandra Sejda, Monika Sakowicz-Burkiewicz, Łukasz Jan Adamski, Giulia Marvaso, Piotr Wychowański, Barbara Alicja Jereczek-Fossa. Any Role of PIK3CA and PTEN Biomarkers in the Prognosis in Oral Squamous Cell Carcinoma?Life 2020; 10(12): 325 doi: 10.3390/life10120325
22
Joanna Pastwińska, Aurelia Walczak-Drzewiecka, Magdalena Łukasiak, Marcin Ratajewski, Jarosław Dastych. Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathwayCell Adhesion & Migration 2020; 14(1): 106 doi: 10.1080/19336918.2020.1764690
23
Ismael Riquelme, Oscar Tapia, Jaime A. Espinoza, Pamela Leal, Kurt Buchegger, Alejandra Sandoval, Carolina Bizama, Juan Carlos Araya, Richard M. Peek, Juan Carlos Roa. The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell LinesPathology & Oncology Research 2016; 22(4): 797 doi: 10.1007/s12253-016-0066-5
24
Yi Cao, Jian-Bo Xiong, Guo-Yang Zhang, Yi Liu, Zhi-Gang Jie, Zheng-Rong Li. RETRACTED: Long Noncoding RNA UCA1 Regulates PRL-3 Expression by Sponging MicroRNA-495 to Promote the Progression of Gastric CancerMolecular Therapy - Nucleic Acids 2020; 19: 853 doi: 10.1016/j.omtn.2019.10.020
25
Neha Merchant, Ganji Purnachandra Nagaraju. Novel therapeutic approaches for gastrointestinal malignanciesDiagnostics and Therapeutic Advances in GI Malignancies 2020; : 1 doi: 10.1007/978-981-15-5471-1_1
26
PUJA KHANNA, PEI JOU CHUA, BOON HUAT BAY, GYEONG HUN BAEG. The JAK/STAT signaling cascade in gastric carcinoma (Review)International Journal of Oncology 2015; 47(5): 1617 doi: 10.3892/ijo.2015.3160
27
Wei Yang, Alexander Raufi, Samuel J. Klempner. Targeted therapy for gastric cancer: Molecular pathways and ongoing investigationsBiochimica et Biophysica Acta (BBA) - Reviews on Cancer 2014; 1846(1): 232 doi: 10.1016/j.bbcan.2014.05.003
28
Sile Chen, Xinhua Zhang, Jianjun Peng, Ertao Zhai, Yulong He, Hui Wu, Chuangqi Chen, Jinping Ma, Zhao Wang, Shirong Cai. VEGF promotes gastric cancer development by upregulating CRMP4Oncotarget 2016; 7(13): 17074 doi: 10.18632/oncotarget.7717
29
Samana Batool, Thomson Joseph, Mushraf Hussain, Miza Vuai, Kavish. Khinsar, Syed Din, Arshad Padhiar, Mintao Zhong, Anhong Ning, Wei Zhang, Jing Cao, Min Huang. LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901International Journal of Molecular Sciences 2018; 19(10): 2986 doi: 10.3390/ijms19102986
30
Oscar Tapia, Ismael Riquelme, Pamela Leal, Alejandra Sandoval, Susana Aedo, Helga Weber, Pablo Letelier, Enrique Bellolio, Miguel Villaseca, Patricia Garcia, Juan Carlos Roa. The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significanceVirchows Archiv 2014; 465(1): 25 doi: 10.1007/s00428-014-1588-4
31
Qingfang Li, Zhihui Li, Ting Luo, Huashan Shi. Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapyMolecular Biomedicine 2022; 3(1) doi: 10.1186/s43556-022-00110-2
32
Hsi-Feng Tu, Kuo-Wei Chang, Wei-Fan Chiang, Chung-Ji Liu, En-Hao Yu, Shou-Tien Liu, Shu-Chun Lin. The frequent co-expression of the oncogenes PIK3CA and PAK1 in oral carcinomasOral Oncology 2011; 47(3): 211 doi: 10.1016/j.oraloncology.2011.01.003
33
Amitabha Ray, Margot P. Cleary. The potential role of leptin in tumor invasion and metastasisCytokine & Growth Factor Reviews 2017; 38: 80 doi: 10.1016/j.cytogfr.2017.11.002
34
Haibo Wang, Yuanyuan Luo, Zewen Chu, Tengyang Ni, Shiya Ou, Xiaojun Dai, Xiaochun Zhang, Yanqing Liu. Poria Acid, Triterpenoids Extracted from Poria cocos, Inhibits the Invasion and Metastasis of Gastric Cancer CellsMolecules 2022; 27(11): 3629 doi: 10.3390/molecules27113629
35
John Maringa Githaka, Leila Pirayeshfard, Ing Swie Goping. Cancer invasion and metastasis: Insights from murine pubertal mammary gland morphogenesisBiochimica et Biophysica Acta (BBA) - General Subjects 2023; 1867(8): 130375 doi: 10.1016/j.bbagen.2023.130375
36
Tao Chen, Xiao-Yue Xu, Ping-Hong Zhou. Emerging molecular classifications and therapeutic implications for gastric cancerChinese Journal of Cancer 2016; 35(1) doi: 10.1186/s40880-016-0111-5
37
Xue-Bin Zhang, Lei Song, Hong-Juan Wen, Xiao-Xue Bai, Zhen-Juan Li, Lian-Jun Ma. Upregulation of microRNA-31 targeting integrin α5 suppresses tumor cell invasion and metastasis by indirectly regulating PI3K/AKT pathway in human gastric cancer SGC7901 cellsTumor Biology 2016; 37(6): 8317 doi: 10.1007/s13277-015-4511-y
38
Lara Alessandrini, Melissa Manchi, Fabrizio Italia, Tiziana Perin, Vincenzo Canzonieri. Gastric Cancer In The Precision Medicine EraCurrent Clinical Pathology 2019; : 155 doi: 10.1007/978-3-030-04861-7_10
39
Le Yu, Jessica Wei, Pengda Liu. Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancerSeminars in Cancer Biology 2022; 85: 69 doi: 10.1016/j.semcancer.2021.06.019
40
Liang Duan, Liwei Ye, Rui Wu, Haiyan Wang, Xueru Li, Huan Li, Shimei Yuan, He Zha, Hui Sun, Yunyuan Zhang, Xian Chen, Yan Zhang, Lan Zhou. Inactivation of the Phosphatidylinositol 3‐Kinase/Akt Pathway is Involved in BMP9‐mediated Tumor‐suppressive Effects in Gastric Cancer CellsJournal of Cellular Biochemistry 2015; 116(6): 1080 doi: 10.1002/jcb.25063
41
Tasuku Matsuoka, Masakazu Yashiro. The Role of PI3K/Akt/mTOR Signaling in Gastric CarcinomaCancers 2014; 6(3): 1441 doi: 10.3390/cancers6031441
42
Hai Yang Yu, Sung Ok Kim, Cheng-Yun Jin, Gi-Young Kim, Wun-Jae Kim, Young Hyun Yoo, Yung Hyun Choi. β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt PathwayBiomolecules & Therapeutics 2014; 22(3): 184 doi: 10.4062/biomolther.2014.026
43
Qiong Wu, Jiali Ma, Jue Wei, Wenying Meng, Yugang Wang, Min Shi. FOXD1‐AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathwayMolecular Oncology 2021; 15(1): 299 doi: 10.1002/1878-0261.12728
44
Siyuan Zhuang, Haocheng Yun, Xu Zhou, Yanjie Li, Sainan Li, Chunming Liu, Yuchi Zhang. Screening, isolation, and activity evaluation of potential xanthine oxidase inhibitors in Poria Cum Radix Pini and mechanism of action in the treatment of gout diseaseJournal of Separation Science 2024; 47(1) doi: 10.1002/jssc.202300505
45
Hong Jun Kim, Suk-young Lee, Sang Cheul Oh. The Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal CancerFrontiers in Physiology 2016; 7 doi: 10.3389/fphys.2016.00168
46
Renata Silva, Débora Ferreira, Lígia R. Rodrigues. Exosome-based delivery of RNAi leads to breast cancer inhibitionJournal of Drug Delivery Science and Technology 2022; 78: 103931 doi: 10.1016/j.jddst.2022.103931
47
Lian-Wen Yuan, Hiroharu Yamashita, Yasuyuki Seto. Glucose metabolism in gastric cancer: The cutting-edgeWorld Journal of Gastroenterology 2016; 22(6): 2046-2059 doi: 10.3748/wjg.v22.i6.2046
48
Xinkui Liu, Jiarui Wu, Dan Zhang, Kaihuan Wang, Xiaojiao Duan, Ziqi Meng, Xiaomeng Zhang. Network Pharmacology-Based Approach to Investigate the Mechanisms ofHedyotis diffusaWilld. in the Treatment of Gastric CancerEvidence-Based Complementary and Alternative Medicine 2018; 2018: 1 doi: 10.1155/2018/7802639