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Cited by in CrossRef
For: Zhao ZH, Xin FZ, Zhou D, Xue YQ, Liu XL, Yang RX, Pan Q, Fan JG. Trimethylamine N-oxide attenuates high-fat high-cholesterol diet-induced steatohepatitis by reducing hepatic cholesterol overload in rats. World J Gastroenterol 2019; 25(20): 2450-2462 [PMID: 31171889 DOI: 10.3748/wjg.v25.i20.2450]
URL: https://www.wjgnet.com/1007-9327/full/v25/i20/2450.htm
Number Citing Articles
1
Hany Ahmed, Quentin Leyrolle, Ville Koistinen, Olli Kärkkäinen, Sophie Layé, Nathalie Delzenne, Kati Hanhineva. Microbiota-derived metabolites as drivers of gut–brain communicationGut Microbes 2022; 14(1) doi: 10.1080/19490976.2022.2102878
2
Gunter Almer, Dietmar Enko, Noora Kartiosuo, Harri Niinikoski, Terho Lehtimäki, Eveliina Munukka, Jorma Viikari, Tapani Rönnemaa, Suvi P Rovio, Juha Mykkänen, Hanna Lagström, Antti Jula, Markus Herrmann, Olli T Raitakari, Andreas Meinitzer, Katja Pahkala. Association of Serum Trimethylamine-N-Oxide Concentration from Childhood to Early Adulthood with Age and SexClinical Chemistry 2024; 70(9): 1162 doi: 10.1093/clinchem/hvae087
3
Julia A. Golubeva, Anna F. Sheptulina, Anastasia Yu. Elkina, Ekaterina O. Liusina, Anton R. Kiselev, Oxana M. Drapkina. Which Comes First, Nonalcoholic Fatty Liver Disease or Arterial Hypertension?Biomedicines 2023; 11(9): 2465 doi: 10.3390/biomedicines11092465
4
Larisse Longo, Pabulo Henrique Rampelotto, Eduardo Filippi-Chiela, Valessa Emanoele Gabriel de Souza, Fernando Salvati, Carlos Thadeu Cerski, Themis Reverbel da Silveira, Cláudia P Oliveira, Carolina Uribe-Cruz, Mário Reis Álvares-da-Silva. Gut dysbiosis and systemic inflammation promote cardiomyocyte abnormalities in an experimental model of steatohepatitisWorld Journal of Hepatology 2021; 13(12): 2052-2070 doi: 10.4254/wjh.v13.i12.2052
5
Ling Zhang, Ning Chen, Libin Zhan, Tingting Bi, Wen Zhou, Lijing Zhang, Lianlian Zhu. Erchen Decoction alleviates obesity-related hepatic steatosis via modulating gut microbiota-drived butyric acid contents and promoting fatty acid β-oxidationJournal of Ethnopharmacology 2023; 317: 116811 doi: 10.1016/j.jep.2023.116811
6
Zhi‐Xiong Lei, Juan‐Juan Wang, Kang Li, Ping Liu. Herp knockout protects against nonalcoholic fatty liver disease in mice on a high fat dietThe Kaohsiung Journal of Medical Sciences 2021; 37(6): 487 doi: 10.1002/kjm2.12349
7
Xin Zhao, Patrick Kwabena Oduro, Wanyu Tong, Yuefei Wang, Xiumei Gao, Qilong Wang. Therapeutic potential of natural products against atherosclerosis: Targeting on gut microbiotaPharmacological Research 2021; 163: 105362 doi: 10.1016/j.phrs.2020.105362
8
Jian Tan, Jemma Taitz, Ralph Nanan, Georges Grau, Laurence Macia. Dysbiotic Gut Microbiota-Derived Metabolites and Their Role in Non-Communicable DiseasesInternational Journal of Molecular Sciences 2023; 24(20): 15256 doi: 10.3390/ijms242015256
9
Vishakha Sharma, Vaibhav Sharma, Shima Shahjouei, Jiang Li, Durgesh Chaudhary, Ayesha Khan, Donna M. Wolk, Ramin Zand, Vida Abedi. At the Intersection of Gut Microbiome and Stroke: A Systematic Review of the LiteratureFrontiers in Neurology 2021; 12 doi: 10.3389/fneur.2021.729399
10
Weiping Wu, Wugao Liu, Huafu Wang, Wei Wang, Weihua Chu, Jing Jin. β-sitosterol inhibits trimethylamine production by regulating the gut microbiota and attenuates atherosclerosis in ApoE–/– miceFrontiers in Cardiovascular Medicine 2022; 9 doi: 10.3389/fcvm.2022.986905
11
Xiaozhuan Lin, Xuan Zhu, Yan Xin, Peiwen Zhang, Yunjun Xiao, Taiping He, Honghui Guo. Intermittent Fasting Alleviates Non‐Alcoholic Steatohepatitis by Regulating Bile Acid Metabolism and Promoting Fecal Bile Acid Excretion in High‐Fat and High‐Cholesterol Diet Fed MiceMolecular Nutrition & Food Research 2023; 67(14) doi: 10.1002/mnfr.202200595
12
Manisha Agarwal, Katherine Roth, Zhao Yang, Rahul Sharma, Krishnarao Maddipati, Judy Westrick, Michael C. Petriello. Loss of flavin-containing monooxygenase 3 modulates dioxin-like polychlorinated biphenyl 126-induced oxidative stress and hepatotoxicityEnvironmental Research 2024; 250: 118492 doi: 10.1016/j.envres.2024.118492
13
Xin Dai, Huiqin Hou, Wanru Zhang, Tianyu Liu, Yun Li, Sinan Wang, Bangmao Wang, Hailong Cao. Microbial Metabolites: Critical Regulators in NAFLDFrontiers in Microbiology 2020; 11 doi: 10.3389/fmicb.2020.567654
14
Simon McArthur. Regulation of Physiological Barrier Function by the Commensal MicrobiotaLife 2023; 13(2): 396 doi: 10.3390/life13020396
15
Fulin Nian, Yueying Chen, Qiaoyun Xia, Chen Zhu, Longyun Wu, Xiaolan Lu. Gut microbiota metabolite trimethylamine N-oxide promoted NAFLD progression by exacerbating intestinal barrier disruption and intrahepatic cellular imbalanceInternational Immunopharmacology 2024; 142: 113173 doi: 10.1016/j.intimp.2024.113173
16
Rajat Giri, Rakesh Kumar Sharma. Analysis of protein association networks regulating the neuroactive metabolites production in Lactobacillus speciesEnzyme and Microbial Technology 2022; 154: 109978 doi: 10.1016/j.enzmictec.2021.109978
17
Vuong Vu, Young Mee Kim, Moonjae Cho. Effects of SCFAs and TMAO on non-alcoholic fatty liver disease indicating the therapeutic benefits of plant-based diet, and supplemental prebiotics, probiotics and synbioticsApplied Biological Chemistry 2023; 66(1) doi: 10.1186/s13765-022-00755-1
18
Monica Simina Mihuta, Corina Paul, Andreea Borlea, Cristina Mihaela Roi, Denisa Pescari, Oana-Alexandra Velea-Barta, Ioana Mozos, Dana Stoian. Connections between serum Trimethylamine N-Oxide (TMAO), a gut-derived metabolite, and vascular biomarkers evaluating arterial stiffness and subclinical atherosclerosis in children with obesityFrontiers in Endocrinology 2023; 14 doi: 10.3389/fendo.2023.1253584
19
Cátia Almeida, J. Guilherme Gonçalves-Nobre, Diogo Alpuim Costa, Pedro Barata. The potential links between human gut microbiota and cardiovascular health and disease - is there a gut-cardiovascular axis?Frontiers in Gastroenterology 2023; 2 doi: 10.3389/fgstr.2023.1235126
20
Xiaoyue Li, Chengcheng Wang, Teruyoshi Yanagita, Changhu Xue, Tiantian Zhang, Yuming Wang. Trimethylamine N-Oxide in Aquatic FoodsJournal of Agricultural and Food Chemistry 2024; 72(26): 14498 doi: 10.1021/acs.jafc.4c01974
21
Fangyu An, Xueru Jia, Yangyang Shi, Xiaolong Xiao, Fan Yang, Junchang Su, Xia Peng, Guangqin Geng, Chunlu Yan. The ultimate microbial composition for correcting Th17/Treg cell imbalance and lipid metabolism disorders in osteoporosisInternational Immunopharmacology 2025; 144: 113613 doi: 10.1016/j.intimp.2024.113613
22
Max S. Z. Zwartjes, Victor E. A. Gerdes, Max Nieuwdorp. The Role of Gut Microbiota and Its Produced Metabolites in Obesity, Dyslipidemia, Adipocyte Dysfunction, and Its InterventionsMetabolites 2021; 11(8): 531 doi: 10.3390/metabo11080531
23
Hong Zou, Lijing Gong, Zhiyuan Wang, Caihua Huang, Yue Luo, Xiao Jia, Jingjing Yu, Donghai Lin, Yimin Zhang. Effects of Trimethylamine N-Oxide in Improving Exercise Performance in Mice: A 1H-NMR-Based Metabolomic Analysis ApproachMolecules 2024; 29(17): 4128 doi: 10.3390/molecules29174128
24
Zhen Li, Xinyi He, Qi Fang, Xulong Yin. Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide and Ischemic StrokeBiomolecules 2024; 14(11): 1463 doi: 10.3390/biom14111463
25
Emily S. Krueger, Joseph L. Beales, Kacie B. Russon, Weston S. Elison, Jordan R. Davis, Jackson M. Hansen, Andrew P. Neilson, Jason M. Hansen, Jeffery S. Tessem. Gut Metabolite Trimethylamine N-Oxide Protects INS-1 β-Cell and Rat Islet Function under Diabetic Glucolipotoxic ConditionsBiomolecules 2021; 11(12): 1892 doi: 10.3390/biom11121892
26
Shengnan Han, Longhui Cai, Peipei Chen, Weihong Kuang. A study of the correlation between stroke and gut microbiota over the last 20years: a bibliometric analysisFrontiers in Microbiology 2023; 14 doi: 10.3389/fmicb.2023.1191758
27
Dengcheng Zhou, Jing Zhang, Chengju Xiao, Chunheng Mo, Bi-Sen Ding. Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitisFrontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.964477
28
Liu Yang, Dan Liu, Hongqin Yan, Kaixia Chen. Dapagliflozin attenuates cholesterol overloading-induced injury in mice hepatocytes with type 2 diabetes mellitus (T2DM) via eliminating oxidative damagesCell Cycle 2022; 21(6): 641 doi: 10.1080/15384101.2022.2031429
29
Sepiso K. Masenga, Joreen P. Povia, Propheria C. Lwiindi, Annet Kirabo. Recent Advances in Microbiota-Associated Metabolites in Heart FailureBiomedicines 2023; 11(8): 2313 doi: 10.3390/biomedicines11082313
30
Zhu-Lin Yu, Lin Ding, Chang-Hu Xue, Tian-Tian Zhang, Yu-Ming Wang. Dietary Trimethylamine N-Oxide Exacerbated Atherosclerosis under a Low-Fat Rather than High-Fat DietJournal of Agricultural and Food Chemistry 2020; 68(25): 6789 doi: 10.1021/acs.jafc.0c03190
31
Hui Han, Yi Jiang, Mengyu Wang, Mebratu Melaku, Lei Liu, Yong Zhao, Nadia Everaert, Bao Yi, Hongfu Zhang. Intestinal dysbiosis in nonalcoholic fatty liver disease (NAFLD): focusing on the gut–liver axisCritical Reviews in Food Science and Nutrition 2023; 63(12): 1689 doi: 10.1080/10408398.2021.1966738
32
Isabela Monique Fortunato, Quélita Cristina Pereira, Fabricio de Sousa Oliveira, Marisa Claudia Alvarez, Tanila Wood dos Santos, Marcelo Lima Ribeiro. Metabolic Insights into Caffeine’s Anti-Adipogenic Effects: An Exploration through Intestinal Microbiota Modulation in ObesityInternational Journal of Molecular Sciences 2024; 25(3): 1803 doi: 10.3390/ijms25031803
33
Beihui He, Jianping Jiang, Zheng Shi, Liyan Wu, Junbin Yan, Zheng Chen, Minmin Luo, Dawei Cui, Sumei Xu, Maoxiang Yan, Shuo Zhang, Zhiyun Chen. Pure total flavonoids from citrus attenuate non-alcoholic steatohepatitis via regulating the gut microbiota and bile acid metabolism in miceBiomedicine & Pharmacotherapy 2021; 135: 111183 doi: 10.1016/j.biopha.2020.111183
34
Shaojun Zhou, Kaiwen Cheng, Yi Peng, Yuxi Liu, Qingqing Hu, Su Zeng, Xuchen Qi, Lushan Yu. Regulation mechanism of endoplasmic reticulum stress on metabolic enzymes in liver diseasesPharmacological Research 2024; 207: 107332 doi: 10.1016/j.phrs.2024.107332
35
Gunter Almer, Maria Donatella Semeraro, Andreas Meinitzer, Dietmar Enko, Giovanny Rodriguez Blanco, Birgit Gallé, Angela Horvath, Christine Moissl-Eichinger, Holger Till, Hans-Jürgen Gruber, Markus Herrmann. Impact of long-term high dietary fat intake and regular exercise on serum TMAO and microbiome composition in female ratsNutrition and Healthy Aging 2023; 8(1): 157 doi: 10.3233/NHA-220198
36
Hui Xiang, Dating Sun, Xin Liu, Zhi-Gang She, Yonghong Chen. The Role of the Intestinal Microbiota in Nonalcoholic SteatohepatitisFrontiers in Endocrinology 2022; 13 doi: 10.3389/fendo.2022.812610
37
Margaret Vourakis, Gaétan Mayer, Guy Rousseau. The Role of Gut Microbiota on Cholesterol Metabolism in AtherosclerosisInternational Journal of Molecular Sciences 2021; 22(15): 8074 doi: 10.3390/ijms22158074
38
Haripriya Gupta, Byeong-Hyun Min, Raja Ganesan, Yoseph Asmelash Gebru, Satya Priya Sharma, Eunju Park, Sung-Min Won, Jin-Ju Jeong, Su-Been Lee, Min-Gi Cha, Goo-Hyun Kwon, Min-Kyo Jeong, Ji-Ye Hyun, Jung-A. Eom, Hee-Jin Park, Sang-Jun Yoon, Mi-Ran Choi, Dong-Joon Kim, Ki-Tae Suk. Gut Microbiome in Non-Alcoholic Fatty Liver Disease: From Mechanisms to Therapeutic RoleBiomedicines 2022; 10(3): 550 doi: 10.3390/biomedicines10030550
39
P. León-Mimila, H. Villamil-Ramírez, X.S. Li, D.M. Shih, S.T. Hui, E. Ocampo-Medina, B. López-Contreras, S. Morán-Ramos, M. Olivares-Arevalo, P. Grandini-Rosales, L. Macías-Kauffer, I. González-González, R. Hernández-Pando, F. Gómez-Pérez, F. Campos-Pérez, C. Aguilar-Salinas, E. Larrieta-Carrasco, T. Villarreal-Molina, Z. Wang, A.J. Lusis, S.L. Hazen, A. Huertas-Vazquez, S. Canizales-Quinteros. Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetesDiabetes & Metabolism 2021; 47(2): 101183 doi: 10.1016/j.diabet.2020.07.010
40
Chin-Yu Liu, Ting-Chia Chang, Shyh-Hsiang Lin, Chih-Wei Tsao. Is a Ketogenic Diet Superior to a High-Fat, High-Cholesterol Diet Regarding Testicular Function and Spermatogenesis?Frontiers in Nutrition 2022; 9 doi: 10.3389/fnut.2022.805794
41
Masaaki Miyata, Kento Takeda, Sayuri Nagira, Yoshimasa Sugiura. Trimethylamine N-oxide ameliorates hepatic damage including reduction of hepatic bile acids and cholesterol in Fxr -null mice International Journal of Food Sciences and Nutrition 2024; 75(4): 385 doi: 10.1080/09637486.2024.2346765
42
Lijun Luo, Yongchun Chang, Li Sheng. Gut-liver axis in the progression of nonalcoholic fatty liver disease: From the microbial derivatives-centered perspectiveLife Sciences 2023; 321: 121614 doi: 10.1016/j.lfs.2023.121614
43
Yinuo Wen, Zefan Sun, Shuoyin Xie, Zixuan Hu, Qicheng Lan, Yupeng Sun, Linbo Yuan, Changlin Zhai. Intestinal Flora Derived Metabolites Affect the Occurrence and Development of Cardiovascular DiseaseJournal of Multidisciplinary Healthcare 2022; : 2591 doi: 10.2147/JMDH.S367591
44
Lesley Hoyles, Matthew G. Pontifex, Ildefonso Rodriguez-Ramiro, M. Areeb Anis-Alavi, Khadija S. Jelane, Tom Snelling, Egle Solito, Sonia Fonseca, Ana L. Carvalho, Simon R. Carding, Michael Müller, Robert C. Glen, David Vauzour, Simon McArthur. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxideMicrobiome 2021; 9(1) doi: 10.1186/s40168-021-01181-z
45
Rachmad Anres Dongoran, Fang-Cen Tu, Chin-Hung Liu. Current insights into the interplay between gut microbiota-derived metabolites and metabolic-associated fatty liver diseaseTzu Chi Medical Journal 2023; 35(4): 290 doi: 10.4103/tcmj.tcmj_122_23
46
YanFei MA, JianXin LIU, HaiFeng WANG. Porcine gut microbiota and lipid metabolism: recent advances and future directionsSCIENTIA SINICA Vitae 2022;  doi: 10.1360/SSV-2021-0363
47
Jiayi Liu, Anding Wu, Jingjing Cai, Zhi-Gang She, Hongliang Li. The contribution of the gut-liver axis to the immune signaling pathway of NAFLDFrontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.968799
48
Kinga Jaworska, Wojciech Kopacz, Mateusz Koper, Marcin Ufnal. Microbiome-Derived Trimethylamine N-Oxide (TMAO) as a Multifaceted Biomarker in Cardiovascular Disease: Challenges and OpportunitiesInternational Journal of Molecular Sciences 2024; 25(23): 12511 doi: 10.3390/ijms252312511
49
Lanlan Fan, Xiaosheng Qu, Tao Yi, Yong Peng, Manjing Jiang, Jianhua Miao, Peigen Xiao, Samra Bashir. Metabolomics of the Protective Effect of Ampelopsis grossedentata and Its Major Active Compound Dihydromyricetin on the Liver of High‐Fat Diet HamsterEvidence-Based Complementary and Alternative Medicine 2020; 2020(1) doi: 10.1155/2020/3472578
50
Qing Fang, Binjie Zheng, Na Liu, Jinfeng Liu, Wenhui Liu, Xinyi Huang, Xiangchang Zeng, Lulu Chen, Zhenyu Li, Dongsheng Ouyang. Trimethylamine N-Oxide Exacerbates Renal Inflammation and Fibrosis in Rats With Diabetic Kidney DiseaseFrontiers in Physiology 2021; 12 doi: 10.3389/fphys.2021.682482
51
Chun Hu, Yumei Zhang, Xiao Bi, Lu Yao, Yueling Zhou, Wei Ding. Correlation between serum trimethylamine- N -oxide concentration and protein energy wasting in patients on maintenance hemodialysis Renal Failure 2022; 44(1): 1670 doi: 10.1080/0886022X.2022.2131572
52
Xi Liang, Zhe Zhang, Youyou Lv, Linjun Tong, Tongjie Liu, Huaxi Yi, Xiaohong Zhou, Zhuang Yu, Xiaoying Tian, Qingyu Cui, Jiebing Yang, Pimin Gong, Lanwei Zhang. Reduction of intestinal trimethylamine by probiotics ameliorated lipid metabolic disorders associated with atherosclerosisNutrition 2020; : 110941 doi: 10.1016/j.nut.2020.110941
53
Andong Zha, Wanquan Li, Jing Wang, Ping Bai, Ming Qi, Peng Liao, Bie Tan, Yulong Yin. Trimethylamine oxide supplementation differentially regulates fat deposition in liver, longissimus dorsi muscle and adipose tissue of growing-finishing pigsAnimal Nutrition 2024; 17: 25 doi: 10.1016/j.aninu.2023.12.006
54
Jae Woong Jang, Emma Capaldi, Tracy Smith, Priyanka Verma, John Varga, Karen J. Ho. Trimethylamine N-oxide: a meta-organismal axis linking the gut and fibrosisMolecular Medicine 2024; 30(1) doi: 10.1186/s10020-024-00895-8
55
Panagiotis Theofilis, Aikaterini Vordoni, Rigas G Kalaitzidis. Interplay between metabolic dysfunction-associated fatty liver disease and chronic kidney disease: Epidemiology, pathophysiologic mechanisms, and treatment considerationsWorld Journal of Gastroenterology 2022; 28(39): 5691-5706 doi: 10.3748/wjg.v28.i39.5691
56
Lin Zhang, Fang Yu, Jian Xia. Trimethylamine N-oxide: role in cell senescence and age-related diseasesEuropean Journal of Nutrition 2022;  doi: 10.1007/s00394-022-03011-w
57
Emily S. Krueger, Trevor S. Lloyd, Jeffery S. Tessem. The Accumulation and Molecular Effects of Trimethylamine N-Oxide on Metabolic Tissues: It’s Not All BadNutrients 2021; 13(8): 2873 doi: 10.3390/nu13082873
58
Cristian Marius Florea, Radu Rosu, Remus Moldovan, Laurian Vlase, Vlad Toma, Nicoleta Decea, Ioana Baldea, Gabriela Adriana Filip. The impact of chronic Trimethylamine N-oxide administration on liver oxidative stress, inflammation, and fibrosisFood and Chemical Toxicology 2024; 184: 114429 doi: 10.1016/j.fct.2023.114429
59
Christopher Papandreou, Margret Moré, Aouatef Bellamine. Trimethylamine N-Oxide in Relation to Cardiometabolic Health—Cause or Effect?Nutrients 2020; 12(5): 1330 doi: 10.3390/nu12051330
60
Emily Connell, Gwénaëlle Le Gall, Simon McArthur, Leonie Lang, Bernadette Breeze, Matthew G. Pontifex, Saber Sami, Line Pourtau, David Gaudout, Michael Müller, David Vauzour. (Poly)phenol-rich grape and blueberry extract prevents LPS-induced disruption of the blood-brain barrier through the modulation of the gut microbiota-derived uremic toxinsNeurochemistry International 2024; 180: 105878 doi: 10.1016/j.neuint.2024.105878