Expression and predictive value of miR-489 and miR-21 in melanoma metastasis

Table 4 Relationship between clinicopathological characteristics of melanoma and miR-21 expression

Variable	n	miR-21	t/F	P-value
Age (yr)			1.984	0.052
≤ 50	23	4.72 ± 2.00
> 50	37	5.84 ± 2.20
Gender			0.582	0.563
Male	30	5.12 ± 1.75
Female	30	5.44 ± 2.45
Tumor size (cm)			0.386	0.873
≤ 2	17	4.99 ± 1.68
> 2	43	5.57 ± 2.52
Lesion site			0.386	0.873
Non-acral	44	5.16 ± 1.55
Acral	16	5.40 ± 2.65
TNM stage			5.040	0.004
I	7	3.60 ± 1.79
II	8	5.23 ± 2.13
III	25	5.28 ± 2.01
IV	20	7.01 ± 2.47
Metastasis			3.295	0.002
Yes	45	6.38 ± 2.35
No	15	4.18 ± 1.85