HLA antigens in individuals with down syndrome and alopecia areata

doi:10.12998/wjcc.v2.i10.541

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World Journal of Clinical Cases

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World J Clin Cases. Oct 16, 2014; 2(10): 541-545
Published online Oct 16, 2014. doi: 10.12998/wjcc.v2.i10.541

Table 2 Distribution of the most frequent human leukocyte antigen A, B, C, DQB1 and DRB1 alleles

Alleles	DS group (A)		AA group (B)		DS + AA group (C)		P value¹
HLA-A 02	4	(40.0)	3	(30.0)	5	(50.0)	0.890
HLA-A 24	1	(10.0)	0	0.0	3	(30.0)	0.290
HLA-A 36	3	(30.0)	0	0.0	0	0.0	0.089
HLA-B 15	4	(40.0)	0	0.0	1	(10.0)	0.094
HLA-B 35	1	(10.0)	2	(20.0)	3	(30.0)	0.850
HLA-B 44	0	0.0	2	(20.0)	4	(40.0)	0.120
HLA-B 53	3	(30.0)	1	(10.0)	1	(10.0)	0.570
HLA-C 02	4	(40.0)	0	0.0	2	(20.0)	0.120
HLA-C 07	4	(40.0)	3	(30.0)	5	(50.0)	0.890
HLA-C 15	1	(10.0)	3	(30.0)	0	0.0	0.290
HLA-DQB1 02	6	(60.0)	3	(30.0)	4	(40.0)	0.530
HLA-DQB1 03	2	(20.0)	6	(60.0)	5	(50.0)	0.270
HLA-DRB1 01	1	(10.0)	2	(20.0)	3	(30.0)	0.850
HLA-DRB1 03	4	(40.0)	3	(30.0)	2	(20.0)	0.880
HLA-DRB1 04	0	0.0	1	(10.0)	2	(20.0)	0.750
HLA-DRB1 11	1	(10.0)	3	(30.0)	3	(30.0)	0.640
HLA-DRB1 13	3	(30.0)	2	(20.0)	4	(40.0)	0.880

¹Fisher Exact test. HLA-A 01, -03, -11, -23, -25, -30, -31, -32, -33, -66, -68, -80. HLA-B 07, -08, -13, -14, -27, -37, -40, -42, -48, -49, - 50, -51, -52,- 57, -58, -81. HLA-C 01, -03,- 04,- 05, -06,- 08, -14,-16,-17. HLA-DQB1 04, -05, -06. HLA-DRB1 01, -07, -08, -10, -12, -15, -16 alleles had a frequency less than 1 and were not included in the Table 2. HLA: Human leukocyte antigen; DS: Down syndrome; AA: Alopecia areata.

Citation: Estefan JL, Oliveira JC, Abad ED, Saintive SB, Porto LCM, Ribeiro M. HLA antigens in individuals with down syndrome and alopecia areata. World J Clin Cases 2014; 2(10): 541-545
URL: https://www.wjgnet.com/2307-8960/full/v2/i10/541.htm
DOI: https://dx.doi.org/10.12998/wjcc.v2.i10.541