HLA antigens in individuals with down syndrome and alopecia areata

Table 1 Demographic and disease variables according the group n (%)

Variable	Category	DS group (A)		AA group (B)		DS + AA group (C)		P value1
Gender	Male	7	(70.0)	7	(70.0)	7	(30.0)	1.000
	Female	3	(30.0)	3	(30.0)	3	(30.0)
Age, mo	Avarage ± SD (median)	224.1 ± 86.0 (233.5)		217.3 ± 90.2 (197.0)		224.3 ± 86.9 (223.5)		0.9702
Clinical presentation	1 lesion S			1	(10.0)	1	(10.0)	Descrip-tive
	1 lesion S/cilium			1	(10.0)	0	0.0
	Lesions S			6	(60.0)	9	(90.0)
	Lesion S/total			1	(10.0)	0	0.0
	Lesion S/total/eyebrow			1	(10.0)	0	0.0
Family history of alopecia	Yes	0	0	2	(20.0)	0	0	0.230
	No	10	(100.0)	8	(80.0)	10	(100.0)
Karyotype	free trisomy	7	(100.0)			6	(85.7)	0.500
	Translocation	0	0			1	(14.3)
Ethnic group	Caucasian	6	(60.0)	3	(30.0)	7	(70.0)	0.270
	Non-Caucasian	4	(40.0)	7	(70.0)	3	(30.0)
Family (n)	0	0	0	2	(20.0)	1	(10.0)	Descrip-tive
	1	3	(30.0)	5	(50.0)	3	(30.0)
	2	2	(20.0)	1	(10.0)	0	0.0
	3	2	(20.0)	1	(10.0)	0	0.0
	4	0	0.0	1	(10.0)	2	(20.0)
	5	1	(10.0)	0	0.0	2	(20.0)
	6	1	(10.0)	0	0.0	1	(10.0)
	7	1	(10.0)	0	0.0	1	(10.0)
Family (n)	Avarage ± SD (median)	3.1 ± 2.2 (2.5)		1.4 ± 1.3 (1)		3.4 ± 2.5 (4)		0.0852

¹Fisher exact test;

²Kruskal-Wallis ANOVA. S: Scalp; DS: Down syndrome; AA: Alopecia areata.