Enzyme replacement therapy in two patients with classic Fabry disease from the same family tree: Two case reports

Figure 3 Microscopic examination (A and B) and electron microscopic examination (C) of cardiac muscles on autopsy. A: Histological findings of the autopsy. Hematoxylin-eosin staining (× 100). Marked vacuolation of the cardiac muscles in the left ventricle wall of the heart. This autopsy finding has been previously published[10]; B: Histological findings in autopsy. Elastica-Masson staining (× 100). Cardiac muscles vacuolation and marked interstitial fibrosis in the left ventricular wall of the heart. This autopsy finding of this case has previously been published[10]; C: Electron microscopic findings in autopsy. Many lamellar structures in the cardiac muscles of the left ventricular wall of the heart (× 6000) observed. This autopsy finding has been previously published[10]. Annotation: These pictures were kindly provided by co-author O. Suzuki, who is the first author of reference[10]. These pictures were not published in their study[10], but were taken for the current study.