Endoscopic submucosal dissection for early signet ring cell gastric cancer: A systematic review and meta-analysis

Table 1 Clinical characteristics of included studies

Ref.	Location (language)	Total patients	Age (yr)	Gender (male/female)	Size; mm	Tumor location	Gross type; n	Ulceration; n
Kang et al[10], 2010	South Korea (English)	30	55.4 ± 11.3	14/16	13.6 ± 5.4	Upper: 0; Middle: 7; Lower: 23	Elevated and flat: 8; Depressed: 19; Mixed: 3	Positive: 7
Choi et al[11], 2013	South Korea (Korean)	27	50.9 ± 11.2	14/13	≤ 10: 8; >10, ≤ 20: 20	Upper: 2; Middle: 13; Lower: 13	Elevated: 5; Flat: 13; Depressed: 10	NA
Kim et al[12], 2014	South Korea (English)	126	55 (range: 28–85)	70/56	< 10: 43; ≥ 10, < 20: 43; ≥ 20: 40	Upper: 9; Middle: 66; Lower: 55	Elevated: 10; Flat: 33; Depressed: 20; Mixed: 63	NA
Jeon et al[13], 2018	South Korea (English)	36	63.6 ± 11.1	14/22	≤ 20: 32; > 20: 4	Upper: 1; Middle: 14; Lower: 21	Elevated: 5; Flat: 8; Depressed: 23	Positive: 0
Horiuchi et al[15], 2018	Japan (English)	129	54.6 ± 11.0	73/56	> 20: 2	Upper: 2; Middle: 13; Lower: 16	Elevated and flat: 8; Depressed: 19; Mixed: 7	Positive: 0
Kwak et al[14], 2018	South Korea (English)	176	52.2 ± 10.8	153/178	NA	NA	Elevated: 39; Flat/Depressed: 292	Positive: 56
Ahn et al[16], 2020	Japan (English)	129	53.6 ± 12.1	52/77	Median (IQR): 12 (10–15)	Upper: 6; Middle: 65; Lower: 58	Elevated: 13; Flat: 13/Depressed: 116	NA

NA: Not applicable.