Dong YP, Deng JY. Advances in para-aortic nodal dissection in gastric cancer surgery: A review of research progress over the last decade. World J Clin Cases 2020; 8(13): 2703-2716 [PMID: 32742981 DOI: 10.12998/wjcc.v8.i13.2703]
Corresponding Author of This Article
Jing-Yu Deng, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology, Tianjin Medical University Cancer Hospital, City Key Laboratory of Tianjin Cancer Center and National Clinical Research Center for Cancer, Huanhuxi Road, Hexi District, Tianjin 300060, China. dengery@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 6, 2020; 8(13): 2703-2716 Published online Jul 6, 2020. doi: 10.12998/wjcc.v8.i13.2703
Advances in para-aortic nodal dissection in gastric cancer surgery: A review of research progress over the last decade
Yin-Ping Dong, Jing-Yu Deng
Yin-Ping Dong, Jing-Yu Deng, Department of Gastroenterology, Tianjin Medical University Cancer Hospital, City Key Laboratory of Tianjin Cancer Center and National Clinical Research Center for Cancer, Tianjin 300060, China
Author contributions: Dong YP wrote the paper; Deng JY designed the research; all authors read and approved the final manuscript.
Supported bythe Programs of National Natural Science Foundation of China, No. 81572372; National Key Research and Development Program “ Major Chronic Non-infectious Disease Research”, No. 2016YFC1303200; and National Key Research and Development Program “ Precision Medicine Research”, No. 2017YFC0908300.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jing-Yu Deng, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology, Tianjin Medical University Cancer Hospital, City Key Laboratory of Tianjin Cancer Center and National Clinical Research Center for Cancer, Huanhuxi Road, Hexi District, Tianjin 300060, China. dengery@126.com
Received: March 4, 2020 Peer-review started: March 4, 2020 First decision: April 12, 2020 Revised: April 30, 2020 Accepted: June 7, 2020 Article in press: June 7, 2020 Published online: July 6, 2020
Core Tip
Core tip: Para-aortic lymph node metastasis is defined as lymph node metastasis between the aortic hiatus and the aortic bifurcation. To date, it is considered a distant metastasis and plays a crucial role in the evaluation of the prognosis of advanced gastric cancer (AGC). The necessity of para-aortic lymph node dissection (PAND) remains uncertain for patients with AGC. Preoperative S-1 and cisplatin followed by radical surgery with D2 + PAND is the current standard treatment strategy for patients with extensive lymph node metastasis. The main purpose of this review is to summarize the advances in the therapeutic effects of PAND in patients with AGC. The second purpose is to highlight the clinical significance of chemotherapy combined with radical surgery for patients with AGC.
