Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2019; 7(21): 3436-3445
Published online Nov 6, 2019. doi: 10.12998/wjcc.v7.i21.3436
Published online Nov 6, 2019. doi: 10.12998/wjcc.v7.i21.3436
Modified Cortex Mori Capsules improving the successful rate of functional filtering blebs after reclinical glaucoma filtering surgery
Jing Yu, Li-Xin Qiu, Guo-Ping Qing, Bo-Wen Zhao, Hui Wang, Beijing Tongren Eye Center, Laboratory of Ophthalmology and Visual Science in Beijing, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Author contributions: Qiu LX designed the research; Yu J, Qiu LX, Qing GP, Zhao BW and Wang H performed the research; Qing GP contributed new reagents/analytic tools; Yu J and Qiu LX analyzed the data; Yu J and Zhao BW wrote the paper.
Institutional review board statement: The study protocol was approved by the institutional review board of Beijing Tongren Hospital in China.
Informed consent statement: The patient involved in this study gave written informed consent.
Conflict-of-interest statement: The authors report no conflicts of interest related to the subject matter of the manuscript.
Data sharing statement: No additional unpublished data are available.
STROBE statement: The authors have revised the manuscript according to the STROBE.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Li-Xin Qiu, MD, PhD, Doctor, Beijing Tongren Eye Center, Laboratory of Ophthalmology and Visual Science in Beijing, Beijing Tongren Hospital, Capital Medical University, NO. 1 Dong Jiao Min Xiang, Dongcheng District, Beijing 100730, China. qiulixin65@163.com
Telephone: +86-10-58269604 Fax: +86-10-58269604
Received: July 12, 2019
Peer-review started: July 16, 2019
First decision: September 9, 2019
Revised: September 27, 2019
Accepted: October 5, 2019
Article in press: October 5, 2019
Published online: November 6, 2019
Peer-review started: July 16, 2019
First decision: September 9, 2019
Revised: September 27, 2019
Accepted: October 5, 2019
Article in press: October 5, 2019
Published online: November 6, 2019
Core Tip
Core tip: Glaucoma is one of the leading causes of irreversible blindness. Trabeculectomy is one of the effective surgical techniques, which creates a new drainage channel, resulting in the formation of a subconjunctival bleb. The major reason for filtering bleb failure or scarring of the bleb site is due to excessive scarring after surgery. In this study, we established that the Modified Cortex Mori Capsules have a propensity to increase functional filtering bleb formation and enhance surgical success rate after glaucoma filtering surgery. Intervening with traditional Chinese medicine could be an effective way for improving surgical success.