Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2019; 7(17): 2438-2449
Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2438
Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2438
Risk factors, clinical features, and short-term prognosis of spontaneous fungal peritonitis in cirrhosis: A matched case-control study
Chun-Hong Huang, Lan-Tian Pang, Li-Chen Xu, Tian-Tian Ge, Qiao-Mai Xu, Zhi Chen, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Author contributions: Huang CH and Pang LT wrote the paper; Pang LT, Ge TT, Xu QM, and Xu LC performed data collection; Xu LC and Huang CH participated in the design of the study and analysed the data; Chen Z conceived the study, participated in study design and coordination, and helped draft the manuscript; Ge TT prepared the figures; all the authors read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the institutional review board of The First Affiliated Hospital, Zhejiang University School of Medicine (No. 17-615).
Informed consent statement: Informed consent for this study was not required because the analysis used anonymous clinical data that were obtained after each patient agreed to be treated by written consent.
Conflict-of-interest statement: The authors declare that no competing interest exists.
Data sharing statement: No additional data are available.
Open-Access: This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhi Chen, MD, PhD, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zjuchenzhi@zju.edu.cn
Telephone: +86-571-86971280
Received: May 14, 2019
Peer-review started: May 14, 2019
First decision: June 9, 2019
Revised: July 12, 2019
Accepted: July 27, 2019
Article in press: July 27, 2019
Published online: September 6, 2019
Peer-review started: May 14, 2019
First decision: June 9, 2019
Revised: July 12, 2019
Accepted: July 27, 2019
Article in press: July 27, 2019
Published online: September 6, 2019
Core Tip
Core tip: Spontaneous fungal peritonitis (SFP) is a less recognized but severe complication in cirrhotic patients. In this retrospective study, we found that patients with SFP exhibited more severe systemic inflammation, higher ascites albumin and polymorphonuclear neutrophils, and a worsened 15-d mortality than patients with spontaneous bacterial peritonitis. Long-term antibiotic administration increases the incidence of SFP, while hepatorenal syndrome and total bilirubin are valuable in predicting short-term mortality.