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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 21, 2022; 10(3): 1024-1031
Published online Jan 21, 2022. doi: 10.12998/wjcc.v10.i3.1024
Published online Jan 21, 2022. doi: 10.12998/wjcc.v10.i3.1024
Concomitant Othello syndrome and impulse control disorders in a patient with Parkinson’s disease: A case report
Tian Xu, Zhao-Sheng Li, Wei Fang, Lan-Xiao Cao, Guo-Hua Zhao, Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 322200, Zhejiang Province, China
Author contributions: Xu T reviewed the literature and drafted the manuscript; Li ZS and Fang W collected the clinical data; Cao LX contributed to manuscript drafting; Zhao GH revised the manuscript for intellectual content; all authors read and approved the final manuscript.
Supported by Zhejiang Province Medical Science and Technology Project , No. 2018KY872 ; and Yiwu Science and Technology Bureau Project , No. 20-3-074 .
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Hua Zhao, MD, Director, Doctor, Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, No. N1 Shangcheng Avenue, Yiwu 322200, Zhejiang Province, China. gzhao@zju.edu.cn
Received: May 31, 2021
Peer-review started: May 31, 2021
First decision: October 16, 2021
Revised: November 3, 2021
Accepted: December 22, 2021
Article in press: December 22, 2021
Published online: January 21, 2022
Peer-review started: May 31, 2021
First decision: October 16, 2021
Revised: November 3, 2021
Accepted: December 22, 2021
Article in press: December 22, 2021
Published online: January 21, 2022
Core Tip
Core Tip: Both Othello syndrome (OS) and impulse control disorders in Parkinson’s disease (PD) may be considered side effects of dopamine agonist therapy. These syndromes may have severe consequences; thus, when clinical features of either syndrome appear, the features of both syndromes should be investigated further. We report the case of a patient with PD, OS, hypersexuality, and binge eating. The syndrome was alleviated after a reduction of the patient’s pramipexole dosage and the addition of quetiapine.