Aydin OC, Aydin S, Guney HZ. Defining the awareness and attitude of the clinicians through pharmacovigilance in Turkey. World J Clin Cases 2023; 11(20): 4865-4873 [PMID: 37583988 DOI: 10.12998/wjcc.v11.i20.4865]
Corresponding Author of This Article
Ozlem Celik Aydin, MD, Doctor, Department of Medical Pharmacology, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey. ozlemclk_89@hotmail.com
Research Domain of This Article
Pharmacology & Pharmacy
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 16, 2023; 11(20): 4865-4873 Published online Jul 16, 2023. doi: 10.12998/wjcc.v11.i20.4865
Defining the awareness and attitude of the clinicians through pharmacovigilance in Turkey
Ozlem Celik Aydin, Sonay Aydin, Hakkı Zafer Guney
Ozlem Celik Aydin, Sonay Aydin, Hakkı Zafer Guney, Department of Medical Pharmacology, Gazi University Faculty of Medicine, Ankara 06500, Turkey
Author contributions: Aydin OC and Guney HZ put forward the concept; Aydin OC was responsible for designing; Guney HZ were responsible for supervision; Aydin S, Aydin OC and Guney HZ did the literature search and reviewed the manuscript critically; Aydin S and Aydin OC were responsible for materials and wrote the manuscript; All authors have read and approved the final manuscript.
Institutional review board statement: This cross-sectional analytical investigation was approved by the Gazi University Clinical Research Ethics Committee, No. 25901600-604.01.01-16.
Informed consent statement: The study included everyone who agreed to participate in the survey.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data will be shared with the relevant parties upon request atozlemclk_89@hotmail.com.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ozlem Celik Aydin, MD, Doctor, Department of Medical Pharmacology, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey. ozlemclk_89@hotmail.com
Received: February 21, 2023 Peer-review started: February 21, 2023 First decision: April 10, 2023 Revised: May 1, 2023 Accepted: June 9, 2023 Article in press: June 9, 2023 Published online: July 16, 2023
ARTICLE HIGHLIGHTS
Research background
The activities and scientific studies conducted to detect, evaluate, understand, or prevent adverse reactions and other drug-related problems constitute pharmacovigilance (PV). There are studies analysing the PV knowledge of healthcare professionals in Turkey and worldwide but more extensive research is required on this topic.
Research motivation
Due to their shared responsibility for PV applications, each healthcare professional must investigate PV with care. The knowledge, attitudes, and actions of healthcare personnel regarding PV can have an immediate effect on patient safety.
Research objectives
In order to assess the knowledge, experience, and perspectives of clinicians regarding PV and reporting adverse drug reactions (ADRs), this study intended to administer a questionnaire to as many physicians from as many institutions as possible.
Research methods
The study was analytical and cross-sectional. Using a questionnaire, data were collected. The questionnaire was emailed out. The survey was sent to 2030 physicians and 670 of them participated.
Research results
PV was correctly defined by 53.9% of participants according to the most accurate definition. The most significant objective of PV was correctly identified by 54.9% of participants. The PV knowledge of nonsurgical physicians was superior to that of surgeons. ADR reporting forms were filled out by 80.9% of physicians who encountered ADRs.
Research conclusions
Insufficient PV knowledge was observed among physicians. The percentage of participants with a favourable attitude toward PV exceeded the percentage of those with a high level of knowledge. Although 50% of physicians had encountered ADRs, the rate of filling out the ADR reporting form was low. The proportion of individuals who received training on how to complete the ADR reporting form was also low.
Research perspectives
The acquired data will be used to identify the problems of physicians in the field of PV, to enhance the current situation, and to serve as a basis for future research in this area.
