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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2022; 10(14): 4460-4469
Published online May 16, 2022. doi: 10.12998/wjcc.v10.i14.4460
Published online May 16, 2022. doi: 10.12998/wjcc.v10.i14.4460
Correlation of pressure gradient in three hepatic veins with portal pressure gradient
Hao-Yu Wang, Department of Oncology, The 9th Clinical Medical College & Beijing Shijitan Hospital, Peking University, Beijing 100038, China
Qing-Kun Song, Division of Clinical Epidemiology and Evidence-Based Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Zhen-Dong Yue, Lei Wang, Zhen-Hua Fan, Yi-Fan Wu, Cheng-Bin Dong, Yu Zhang, Department of Interventional Therapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Ming-Ming Meng, Department of Gastroenterology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Ke Zhang, Li Jiang, Department of General Surgery, Beijing Ditan Hospital, Capital Medical University, Beijing 100102, China
Hui-Guo Ding, Yue-Ning Zhang, Department of Gastroenterology and Hepatology, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China
Yong-Ping Yang, Department of Therapeutic Research for Liver Cancer, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China
Fu-Quan Liu, Department of Oncology, The 9th Clinical Medical College & Beijing Shijitan Hospital, Peking University, Beijing 100038, China
Author contributions: Liu FQ, Yue ZD, and Wang L contributed to the conception of the study; Liu FQ and Fan ZH performed the experiments; Wang HY, Meng MM, Zhang K, Jiang L, Ding HD, Zhang YN, and Yang YP contributed significantly to data analysis and manuscript preparation; Wang HY and Song QK performed the data analyses and wrote the manuscript; Wu YF, Dong CB, and Zhang Y helped perform the data analysis.
Supported by Special Scientific Research Project for Health Development in the Capital , No. 2018-1-2081 ; and Scientific Research Common Program of Beijing Municipal Commission of Education , No. KM201810025028 .
Institutional review board statement: The study was reviewed and approved by the Beijing Shijitan Hospital Institutional Review Board.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author atlfuquan@aliyun.com.cn . Participants gave informed consent for data sharing. No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fu-Quan Liu, BCPS, MD, Director, Professor, Department of Interventional Therapy, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian, Haidian District, Beijing 100038, China. lfuquan@aliyun.com
Received: November 26, 2021
Peer-review started: November 26, 2021
First decision: January 11, 2022
Revised: January 25, 2022
Accepted: March 26, 2022
Article in press: March 26, 2022
Published online: May 16, 2022
Peer-review started: November 26, 2021
First decision: January 11, 2022
Revised: January 25, 2022
Accepted: March 26, 2022
Article in press: March 26, 2022
Published online: May 16, 2022
ARTICLE HIGHLIGHTS
Research background
The prognosis of portal hypertension (PHT) with high mortality is directly related to the accuracy of the measured portal pressure.
Research motivation
To improve the prognosis of PHT.
Research objectives
To identify which of the three hepatic veins that can more accurately represent portal pressure.
Research methods
The pressure in three hepatic veins in 102 patients with PHT of different etiologies was measured and compared with their mean portal pressure.
Research results
Correlation of portal pressure gradient (PPG) and hepatic venous pressure gradient is higher in the middle hepatic vein.
Research conclusions
The measurement of pressure in the middle hepatic vein could better represent PPG than the pressure in the left and right hepatic veins.
Research perspectives
Considering the high success rate of clinical measurement of the right hepatic vein, it can be the second choice.