Epigenetics and DNA methylation in cancer

doi:10.5528/wjtm.v4.i1.11

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Apr 12, 2015 (publication date) through Feb 2, 2025

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World Journal of Translational Medicine

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2220-6132

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transl Med. Apr 12, 2015; 4(1): 11-24
Published online Apr 12, 2015. doi: 10.5528/wjtm.v4.i1.11

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Figure 12 Different classes of epigenetic drugs could inhibit epithelial-mesenchymal transition which plays a crucial role in tumor progression generating both mesenchymal differentiated and stem cancer cells. HDACi: Histone deacetylase inhibitor; DNMTi: DNA methyltransferase inhibitor; 5’Aza-C: 5-azacytidine are given as examples of demethylating agent. Adapetd by Kiesslich et al[11], 2013.

Citation: Lattanzio L, Lo Nigro C. Epigenetics and DNA methylation in cancer. World J Transl Med 2015; 4(1): 11-24
URL: https://www.wjgnet.com/2220-6132/full/v4/i1/11.htm
DOI: https://dx.doi.org/10.5528/wjtm.v4.i1.11