Epigenetics and DNA methylation in cancer

doi:10.5528/wjtm.v4.i1.11

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Apr 12, 2015 (publication date) through Nov 13, 2024

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World Journal of Translational Medicine

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2220-6132

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transl Med. Apr 12, 2015; 4(1): 11-24
Published online Apr 12, 2015. doi: 10.5528/wjtm.v4.i1.11

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Figure 7 The figure represents the general change of global DNA methylation after radiation exposure in cancer cells. Radiation might induce a decrease in DNA methyltransferases, including DNA methyltransferase 1 (DNMT1), DNMT3a, DNMT3b, and methyl CpG binding protein 2 leading to global DNA hypomethylation and genomic instability. Adapted by Kim et al[6], 2013.

Citation: Lattanzio L, Lo Nigro C. Epigenetics and DNA methylation in cancer. World J Transl Med 2015; 4(1): 11-24
URL: https://www.wjgnet.com/2220-6132/full/v4/i1/11.htm
DOI: https://dx.doi.org/10.5528/wjtm.v4.i1.11