Epigenetics and DNA methylation in cancer

doi:10.5528/wjtm.v4.i1.11

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Apr 12, 2015 (publication date) through Nov 28, 2024

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World Journal of Translational Medicine

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2220-6132

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transl Med. Apr 12, 2015; 4(1): 11-24
Published online Apr 12, 2015. doi: 10.5528/wjtm.v4.i1.11

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Figure 5 Molecular regulators regulating epithelial vs mesenchymal cell phenotypes and reverse process. In gray/italicised factors/processes involved in epigenetic control are highlighted. ac: Acetylation; EMT: Epithelial-mesenchymal transition; MET: Mesenchymal-epithelial transition; miR: miRNA; m3: Trimethylation; Shh: Sonic hedgehog; TGFβ: Transforming growth factor beta; KLF4: Kruppel-like transcription factor4; HDAC: Histone deacetylase inhibitor; LSD1: Lysine-specific demethylase 1. Adapted by Kiesslich et al[11], 2013.

Citation: Lattanzio L, Lo Nigro C. Epigenetics and DNA methylation in cancer. World J Transl Med 2015; 4(1): 11-24
URL: https://www.wjgnet.com/2220-6132/full/v4/i1/11.htm
DOI: https://dx.doi.org/10.5528/wjtm.v4.i1.11