Insulin receptors in the kidneys in health and disease

Figure 3 Altered natriuresis and impaired nitric oxide metabolism in insulin receptor-knockout mice. A: Urinary sodium excretion after oral administration of saline with and without dextrose in 4 h; B: Mean arterial blood pressure (ΔMAP) after NaCl and dextrose administration in mice; C: Urinary nitrate and nitrite excretion in wild-type and insulin receptor-knockout mice after 24 h. (Figure is a modification of figures published in reference[19] and taken with permission).