Influence of tacrolimus metabolism rate on renal function after solid organ transplantation

Figure 2 Estimated renal function measured by estimated glomerular filtration rate (Cockcroft-Gault eGFR, mL/min) after liver transplantation. There was no noticeable difference between fast and slow tacrolimus metabolizers at liver transplantation at 1 mo or 3 mo after liver transplantation. After 6, 12, and 36 mo, slow tacrolimus metabolizers had a significantly better renal function than fast metabolizers. Mean estimates and corresponding 95% confidence intervals from the multivariable linear mixed model are plotted; overlapping areas are shown in dark grey[59]. eGFR: Estimated glomerular filtration rate.