Pharmacological Tie2 activation in kidney transplantation

Figure 2 Vasculotide-treated mice show less infiltration of inflammatory cells in the kidney. A: Exemplary PAS staining of kidneys from mice treated with vehicle or VT. Glomerular injury was evaluated on day 28 after transplantation; B: Semi-quantification of glomerular injury by surveying kidney cross-sections. Scoring was done as described above (see Table 1) (vehicle n = 3; VT n = 5) (^aP < 0.05); C: PAS staining for peritubular injury in transplanted kidneys from mice treated with vehicle or VT; D: Semi-quantification of interstitial inflammation by surveying kidney cross-sections from transplanted mice (^aP < 0.05). Scoring was done as described above (Table 1) (vehicle n = 3; VT n = 5). Semi-quantification was assessed using Mann-Whitney test. VT: Vasculotide; PAS: Periodic acid Schiff.