Pulmonary arterial hypertension associated with systemic sclerosis: Current diagnostic approach and therapeutic strategies

Figure 1 Algorithm for detection of pulmonary arterial hypertension in patients with systemic sclerosis. Proposed algorithm for performance of routine clinical tests in patients with systemic sclerosis, which may allow early detection of pulmonary arterial hypertension or other causes of cardiac dysfunction (e.g. left ventricular diastolic or systolic dysfunction). DLCO: Diffusing capacity of carbon monoxide; FVC: Forced vital capacity; PH: Pulmonary hypertension; RHC: Right heart catheterization; RV: Right ventricle; TRV: Tricuspid regurgitation velocity. Reproduced with permission from Hassoun[40].