Three-dimensional stereotactic surface projection in the statistical analysis of single photon emission computed tomography data for distinguishing between Alzheimer’s disease and depression

Figure 1 The three-dimensional stereotactic surface projection results of two representative cases. A: Female, 59 years old; MMSE 26, HAM-D 18, CGI 3; showed significant reduction of perfusion in the AD-associated region (the superior parietal lobule and posterior cingulate gyrus); B: Female, 64 years old; MMSE 28, HAM-D 9, CGI 2; showed significant reduction of perfusion in the depression-associated region (the inferior frontal gyrus). HAM-D: Hamilton Rating Scale for Depression; MMSE: Minimal Mental State Examination; CGI: Clinical Global Impression; AD: Alzheimer’s disease.