Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study

Table 2 Mental disorders regressed on infectious, atopic and inflammatory diseases, odds-ratios and 95%CI derived from logistic regression models

	Model 1 Neurodevelopmental disorders	Model 2 Early anxiety disorders	Model 3 Late anxiety disorders	Model 4 Mood disorders	Model 5 Substance abuse/ dependence
Sex	0.38 (0.27-0.52)	1.60 (1.33-1.94)	1.50 (1.19-1.87)	2.05 (1.74-2.41)	0.19 (0.14-0.24)
Education level
Low	1 (ref)	1 (ref)	1 (ref)	1 (ref)	1 (ref)
Medium	0.91 (0.66-1.24)	1.24 (1.01-1.52)	1.11 (0.87-1.41)	0.86 (0.72-1.04)	1.19 (0.92-1.54)
High	1.10 (0.78-1.56)	1.08 (0.87-1.34)	1.07 (0.83-1.39)	0.88 (0.72-1.06)	1.27 (0.98-1.66)
Familial aggregation of CMD	1.55 (1.07-2.23)	2.54 (2.14-3.01)	1.75 (1.34-2.29)	1.77 (1.52-2.06)	2.12 (1.59-2.82)
Trauma below age of 10	1.43 (0.84-2.44)	1.07 (0.73-1.57)	1.12 (0.73-1.71)	1.11 (0.76-1.62)	1.36 (0.84-2.20)
Childhood adversities	2.74 (2.09-3.60)	1.51 (1.25-1.81)	1.89 (1.53-2.33)	1.87 (1.57-2.23)	1.81 (1.45-2.27)
Streptococcal infections	1.29 (0.79-2.10)	1.11 (0.80-1.55)	1.22 (0.84-1.78)	0.80 (0.59-1.10)	0.80 (0.51-1.25)
Mumps, measles, rubella	1.37 (0.91-2.06)	1.36 (1.04-1.77)	1.33 (0.97-1.83)	1.07 (0.86-1.34)	1.15 (0.85-1.54)
Peptic ulcer/gastritis	1.72 (1.11-2.68)	1.23 (0.89-1.71)	1.47 (1.03-2.11)	1.74 (1.27-2.39)	1.58 (1.09-2.29)
Irritable bowel syndrome	1.30 (0.71-2.36)	1.81 (1.24-2.64)	1.74 (1.15-2.62)	1.87 (1.26-2.79)	1.70 (1.06-2.73)
Atopic diseases	0.95 (0.73-1.25)	1.11 (0.94-1.31)	1.24 (1.01-1.51)	1.06 (0.91-1.24)	1.02 (0.83-1.26)
Acne	0.83 (0.53-1.30)	1.10 (0.85-1.43)	1.02 (0.74-1.39)	1.23 (0.97-1.57)	1.27 (0.92-1.76)
Psoriasis	1.22 (0.69-2.16)	1.45 (0.99-2.11)	1.05 (0.66-1.69)	1.59 (1.11-2.28)	1.41 (0.91-2.19)
Urinary tract infections	1.51 (1.06-2.14)	1.37 (1.12-1.67)	1.06 (0.83-1.35)	1.49 (1.22-1.80)	1.20 (0.88-1.64)

CMD: Common mental disorders.