Isotretinoin was not associated with depression or anxiety: A twelve-week study

Table 6 Demographic and clinical features of the subjects who developed clinically significant depression or anxiety

Treatment	Age (yr)	Gender	Personal history of depression	Personal history of anxiety	Diagnosis before treatment (categorical Zung scales)	Diagnosis during treatment (categorical Zung scales)
ITT	18	M	Yes	Yes	-	Anxiety
ITT	28	M	No	Yes	Anxiety and depression	Anxiety and depression
ITT	25	F	No	No	-	Anxiety and depression
ITT	23	F	Yes	No	-	Anxiety
ITT	23	F	No	No	Depression	Depression
OT	18	M	Yes	Yes	Anxiety and depression	Anxiety and depression
OT	24	M	Yes	No	Depression	Depression

ITT: Isotretinoin; OT: Other treatments; F: Female; M: Male.