Sensation/novelty seeking in psychotic disorders: A review of the literature

Table 3 Sensation/novelty seeking and quality of life

Ref.	n	Trait-instrument	Main findings
Hansson et al[37]	104 outpatients with schizophrenia, schizophreniform disorder, or schizoaffective disorder	NS, TCI	Several personality dimensions, but not NS were correlated to subjective quality of life
Ritsner et al[38]	90 inpatients and outpatients with schizophrenia Drug/alcohol abuse was an exclusion criterion	NS, TPQ	Higher levels of NS were associated with better general quality of life
Kurs et al[39]	47 schizophrenia outpatients, 47 non-affected siblings 56 healthy subjects Drug/alcohol abuse was an exclusion criterion	NS, TPQ	Harm avoidance but not NS was associated with general quality of life. There were no differences in NS between patients, siblings and controls
Margetić et al[40]	120 schizophrenia outpatients 120 first degree relatives 129 healthy controls History of drug/alcohol dependence was an exclusion criterion	NS, TCI	Quality of life was not related to NS. Patients scored lower on NS compared to controls, and similar to relatives
Jetha et al[41]	41 outpatients with schizophrenia spectrum disorders 41 healthy controls	NS, TCI	NS was not related to any aspect of quality of life. Patients had significantly lower scores on NS than controls

NS: Novelty seeking; TPQ: Tridimensional personality questionnaire; TCI: Temperament and character inventory.