Link of gray matter volume to cognitive and motor function in elderly patients with mild cognitive impairment

Table 1 Comparison of clinical characteristics, neuropsychology, and gait parameters between normal control group and amnestic mild cognitive impairment group

Item	NC group (n = 45)	aMCI group (n = 45)	Z/t/χ2	P value
Gender [male (%)]	21 (46.67)	23 (51.11)	0.178	0.673
Age (years)	66.15 ± 8.06	65.97 ± 8.45	0.103	0.919
BMI index (kg/m2)	23.84 ± 2.68	23.54 ± 3.05	0.501	0.618
Smoke, n (%)	5 (11.11)	9 (20.00)	1.353	0.245
Heart disease, n (%)	8 (17.78)	6 (13.33)	0.338	0.561
Diabetes mellitus, n (%)	6 (13.33)	8 (17.78)	0.338	0.561
MMSE, [M (P25, P75)]	32 (30, 33)	25 (23, 27)	-5.124	0.000
MoCA, [M (P25, P75)]	29 (28, 31)	21 (19, 33)	-6.051	0.000
CAMCOG-C, [M (P25, P75)]	93 (90, 97)	76 (72, 81)	-6.315	0.000
GDS, [M (P25, P75)]	6 (3, 8)	8 (5, 10)	-2.012	0.046
ADL, [M (P25, P75)]	20 (19, 21)	20 (20, 21)	-1.548	0.140
TUG (s)	11.35 ± 2.35	13.94 ± 2.64	-4.916	0.000
D-TUG (s)	12.02 ± 2.64	15.06 ± 2.10	-6.054	0.000
BBS, [M (P25, P75)]	56 (54, 57)	54 (53, 56)	-2.458	0.006
Step length (m)	0.57 ± 0.04	0.50 ± 0.08	5.582	0.000
Leg speed (m/s)	1.08 ± 0.13	0.94 ± 0.18	4.249	0.000
Step frequency (steps/min)	108.15 ± 7.84	103.11 ± 12.05	2.350	0.021

aMCI: Amnestic mild cognitive impairment; MMSE: Mini-Mental State Examination; MoCA: Montreal Cognitive Assessment Scale; CAMCOG-C: Cambridge Cognitive Examination-Chinese Version; ADL: Activities of Daily Living; TUG: Time Up and Go Test; D-TUG: Dual Task of Time Up and Go Test; BBS: Berg Balance Scale.