Nutritional status of elderly hypertensive patients and its relation to the occurrence of cognitive impairment

Table 8 Comparison of clinical data between the two groups of patients with different cognitive functions in the validation cohort, n (%)

Norm	Total cases (n = 60)	Hypertension combined with cognitive impairment group (n = 14)	Cognitively normal group with hypertension (n = 46)	t/χ2/F	P value
Distinguishing between the sexes				0.034	0.854
Male	27 (45.00)	6 (42.86)	21 (45.65)
Women	33 (55.00)	8 (57.14)	25 (54.35)
Age, year	71.44 ± 7.23	72.81 ± 8.14	70.66 ± 7.15	9.540	0.344
BMI, kg/m2	22.52 ± 2.61	20.12 ± 2.94	24.68 ± 2.41	5.885	0.000
Family history of hypertension				3.375	0.066
Yes	24 (40.00)	7 (50.00)	17 (36.96)
No	36 (60.00)	7 (50.00)	29 (63.04)
Course of hypertension, year	9.71 ± 3.10	10.29 ± 3.66	8.23 ± 3.14	2.068	0.043
High blood pressure classification				0.059	0.953
Level 1	34 (56.67)	8 (57.14)	26 (56.52)
Level 2	16 (26.67)	3 (18.75)	13 (28.26)
Level 3	10 (16.67)	3 (18.75)	7 (15.22)
Drinking history				0.066	0.798
Yes	21 (35.00)	5 (35.71)	16 (34.78)
No	39 (65.00)	9 (64.29)	30 (65.22)
Smoking history				0.034	0.854
Yes	33 (55.00)	8 (57.14)	25 (54.35)
No	27 (45.00)	6 (42.86)	21 (45.65)
Defatted body weight, kg	54.46 ± 8.59	54.65 ± 8.28	55.71 ± 9.12	0.389	0.699
Upper arm muscle dimension, cm	24.88 ± 3.11	25.01 ± 2.08	24.13 ± 2.35	1.257	0.214
ALB, g/L	37.76 ± 3.62	36.22 ± 3.58	39.71 ± 4.68	2.565	0.013
Hb, g/L	134.47 ± 11.57	123.27 ± 12.32	141.39 ± 11.27	5.156	0.000
AST, U/L	20.35 ± 3.31	20.21 ± 3.25	20.42 ± 3.40	0.204	0.839
ALT, U/L	17.87 ± 2.81	17.74 ± 2.81	17.91 ± 2.86	0.196	0.846
Cr, mmol/L	80.43 ± 20.22	82.11 ± 19.10	78.85 ± 22.14	0.497	0.621
Hcy, mmol/L	20.42 ± 7.31	22.92 ± 6.83	19.11 ± 7.38	1.719	0.091
UA, μmol/L	259.68 ± 65.97	252.63 ± 61.02	265.63 ± 75.27	0.589	0.558
ALP, U/L	119.57 ± 19.71	122.85 ± 18.57	102.41 ± 22.05	3.141	0.003
Absolute lymphocytes	1.49 ± 0.65	1.44 ± 0.62	1.53 ± 0.66	0.453	0.652
TC, mmol/L	3.94 ± 0.81	3.98 ± 0.78	4.14 ± 0.80	0.659	0.513
TG, mmol/L	1.30 ± 0.62	1.41 ± 0.59	1.32 ± 0.63	0.475	0.637
LDL-C, mmol/L	1.15 ± 0.46	1.16 ± 0.33	1.12 ± 0.35	0.379	0.706
HDL-C, mmol/L	2.45 ± 0.77	2.38 ± 0.82	2.47 ± 0.76	0.381	0.705
MNA score, cent	21.74 ± 3.08	17.92 ± 3.41	22.88 ± 2.61	5.785	0.000

BMI: Body mass index; ALB: Albumin; Hb: Hemoglobin; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; Cr: Creatinine; Hcy: Homocysteine; UA: Uric acid; ALP: Alkaline phosphatase; TC: Total cholesterol: TG: Triglycerides; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol; MNA: Mini-Nutritional Assessment Scale.