Association and functional study of ATP6V1D and GPHN gene polymorphisms with depression in Chinese population

doi:10.5498/wjp.v15.i4.102182

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Apr 19, 2025 (publication date) through Mar 28, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Apr 19, 2025; 15(4): 102182
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.102182

Table 5 Haplotype analysis of the rs10144417, rs2031564, rs3759755, rs8016024 and rs8020095 with the depression, n (%)

Haplotype	Patients	Control	OR (95%CI)	P value (dimensionless)
Haplotype	2n = 1110 (%)	2n = 1018 (%)	OR (95%CI)	P value (dimensionless)
AGATG	536 (48.3)	468 (46.0)	1.000	-
GACCA	437 (39.4)	421 (41.4)	0.906 (0.755-1.008)	0.291
AAACG	52 (4.7)	33 (3.2)	1.376 (0.874-2.165)	0.166
AGATA	28 (2.5)	43 (4.2)	0.569 (0.348-0.930)	0.023

Haploid types with a population frequency lower than 0.02 were excluded from the study. OR: Odds ratio; CI: Confidence interval.

Citation: Liang P, Chen JJ, Yang X, Long R, Li Y, Wang ZL, Yang PL, Liang YD. Association and functional study of ATP6V1D and GPHN gene polymorphisms with depression in Chinese population. World J Psychiatry 2025; 15(4): 102182
URL: https://www.wjgnet.com/2220-3206/full/v15/i4/102182.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i4.102182