Association and functional study of ATP6V1D and GPHN gene polymorphisms with depression in Chinese population

Table 4 Stratified analyses of the rs3759755, rs10144417, rs2031564, rs8020095 and rs8016024 polymorphisms with depression risk, n (%)

Variables	Frequency		OR (95%CI)1	P value
rs8020095
Depressive episode	Severe	Mild	-	-
G/G	81 (29.1)	83 (30.0)	1.00 (Ref)	-
G/A-A/A	197 (70.9)	194 (70.0)	0.89 (0.61-1.29)	0.54
Suicide attempt	Yes	No	-	-
G/G	81 (25.7)	83 (34.6)	1.00 (Ref)	-
G/A-A/A	234 (74.3)	15 (65.4)	0.73 (0.50-1.07)	0.11
First-episode patient	Yes	No	-	-
G/G	80 (28.6)	84 (30.7)	1.00 (Ref)	-
G/A-A/A	200 (71.4)	190 (69.3)	1.00 (0.69-1.46)	1.00
Family history	Yes	No	-	-
G/G	28 (27.7)	136 (30.0)	1.00 (Ref)	-
G/A-A/A	73 (72.3)	318 (70.0)	0.95 (0.58-1.54)	0.82
rs10144417
Depressive episode	Severe	Mild	-	-
A/A	97 (34.9)	98 (35.4)	1.00 (Ref)	-
A/G-G/G	181 (65.1)	179 (64.6)	0.94 (0.66-1.34)	0.75
Suicide attempt	Yes	No	-	-
A/A	104 (33.0)	91 (37.9)	1.00 (Ref)	-
A/G-G/G	211 (67.0)	149 (62.1)	0.85 (0.59-1.23)	0.39
First-episode patient	Yes	No	-	-
A/A	99 (35.4)	96 (34.9)	1.00 (Ref)	-
A/G-G/G	181 (64.6)	179 (65.1)	1.08 (0.75-1.54)	0.67
Family history	Yes	No	-	-
A/A	32 (31.7)	163 (35.9)	1.00 (Ref)	-
A/G-G/G	69 (68.3)	291 (64.1)	0.85 (0.54-1.36)	0.50

¹Odds ratio was adjusted by age and gender.

OR: Odds ratio; CI: Confidence interval.