Using the THINC-integrated tool to compare the characteristics of cognitive dysfunction in patients with unipolar and bipolar depression

Table 3 Comparison of cognitive function between unipolar and bipolar depression and healthy controls

Item	MDD (n = 75)	BD-D (n = 120)	HC (n = 100)	F	P value
Spotter	-0.485 ± 1.215	-0.089 ± 0.906	0.440 ± 0.732	20.861	< 0.001
Symbol check	0.006 ± 0.955	-0.085 ± 1.093	0.094 ± 0.916	0.871	0.419
Codebreaker	-0.349 ± 1.097	-0.058 ± 1.049	0.305 ± 0.759	9.671	< 0.001
Trails	-0.047 ± 0.654	-0.218 ± 1.379	0.291 ± 0.445	7.480	0.001
PDQ-5-D	-0.714 ± 0.907	-0.025 ± 1.019	0.539 ± 0.666	41.471	< 0.001
THINC-it	-0.318 ± 0.652	-0.095 ± 0.671	0.334 ± 0.401	28.042	< 0.001

P < 0.05 indicates a statistically significant difference. MDD: Major depressive disorder; BD-D: Bipolar depression; HC: Healthy controls; PDQ-5-D: Perceived Deficits Questionnaire for Depression-5-item; THINC-it: The THINC-integrated tool.