Serum homocysteine showed potential association with cognition and abnormal gut microbiome in major depressive disorder

Figure 3 Relative abundance. A: Comparison of relative abundances between healthy controls and major depressive disorder groups. The top 20 operational taxonomic units with the highest abundance and differences were selected; B: The top 20 functional pathways with the highest abundance and differences. The functional pathways were selected using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States 2. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. ^dP < 0.0001. OTU: Operational taxonomic units; MDD: Major depressive disorder; HC: Healthy control.