Voxel-based alterations in spontaneous brain activity among very-late-onset schizophrenia-like psychosis: A preliminary resting-state functional magnetic resonance imaging study

Figure 3 Scatter plots show partial correlations between indices of brain function and cognitive function and clinical symptom severity in very-late-onset schizophrenia-like psychosis, with age, sex, education, and head motion as covariates. A: The amplitude of low-frequency fluctuations values in the right precuneus were negatively correlated with the Mini Mental State Examination score; B: The amplitude of low-frequency fluctuations values in the right precuneus were negatively correlated with the Positive and Negative Syndrome Scale positive subscale score; C: The voxel-mirrored homotopic connectivity (VMHC) values in the bilateral calcarine fissure and surrounding cortex (CAL, clusters C and D, which have the same VMHC values) were negatively correlated with the Repeatable Battery for the Assessment of Neuropsychological Status total score; D: The VMHC values in the bilateral CAL (clusters C and D) were negatively correlated with the Repeatable Battery for the Assessment of Neuropsychological Status delayed memory score; E: The VMHC values in the bilateral CAL (clusters C and D) were negatively correlated with the Positive and Negative Syndrome Scale positive subscale score. MMSE: Mini Mental State Examination; ALFF: Amplitude of low-frequency fluctuations; PCUN.R: Right precuneus; PANSS: Positive and Negative Syndrome Scale; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status; VMHC: Voxel-mirrored homotopic connectivity; CAL: Calcarine fissure and surrounding cortex.