Cumulative effects of stress-sensitivity factors on depressive symptoms and suicide risk: A prospective study

doi:10.5498/wjp.v15.i2.99996

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Feb 19, 2025 (publication date) through Jan 17, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Feb 19, 2025; 15(2): 99996
Published online Feb 19, 2025. doi: 10.5498/wjp.v15.i2.99996

Table 3 Association of the number of high-level stress-sensitivity factors with clinical manifestations and follow-up outcomes in major depressive disorders

Items	Time	All factors Partial eta-squared (η²)	Sig.	PSS + S-AI Partial eta-squared (η²)	Sig.	Neuroticism + T-AI partial eta-squared (η²)	Sig.
HAMD-17	Baseline	0.158	< 0.001^a	0.153	< 0.001^a	0.085	< 0.001^a
HAMD-17	At the end of follow-up	NA	NA	NA	NA	0.204	< 0.001^a
HAMA	Baseline	0.145	< 0.001^a	0.129	< 0.001^a	0.072	< 0.001^a
HAMA	At the end of follow-up	NA	NA	NA	NA	0.155	< 0.001^a
BSSI	Baseline	0.160	< 0.001^a	0.117	< 0.001^a	0.135	< 0.001^a
BSSI	At the end of follow-up (n = 66)	NA	NA	NA	NA	0.156	0.002^a
SDS	Baseline	0.240	< 0.001^a	0.132	< 0.001^a	0.145	< 0.001^a
SDS	At the end of follow-up	NA	NA	NA	NA	0.072	0.003^a
PDQ-5	Baseline	0.138	< 0.001^a	0.065	< 0.001^a	0.066	< 0.001^a
PDQ-5	At the end of follow-up	NA	NA	NA	NA	0.143	< 0.001^a

^aP < 0.05.

The effect size is classified as small (0.01-0.05), medium (0.06-0.13), and large (≥ 0.14) based on Partial η². HAMD-17: 17-item Hamilton Depression Scale; HAMA: Hamilton Anxiety Scale; BSSI: Beck Scale for Suicide Ideation; SDS: Sheehan Disability Scale; PDQ-5: Perceived Deficits Questionnaire five-item version; NA: Not available.

Citation: Qin XM, Xu MQ, Qin YQ, Shao FZ, Ma MH, Ou WW, Lv GY, Zhang QQ, Chen WT, Zhao XT, Deng AQ, Xiong JT, Zeng LS, Peng YL, Huang M, Xu SY, Liao M, Zhang L, Li LJ, Ju YM, Liu J, Liu BS, Zhang Y. Cumulative effects of stress-sensitivity factors on depressive symptoms and suicide risk: A prospective study. World J Psychiatry 2025; 15(2): 99996
URL: https://www.wjgnet.com/2220-3206/full/v15/i2/99996.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i2.99996