Integrative transcriptomic and proteomic analysis reveals that SERPING1 inhibits neuronal proliferation via the CaMKII-CREB-BDNF pathway in schizophrenia

doi:10.5498/wjp.v15.i2.100214

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Feb 19, 2025 (publication date) through Jan 29, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Feb 19, 2025; 15(2): 100214
Published online Feb 19, 2025. doi: 10.5498/wjp.v15.i2.100214

Table 4 Differential gene expression statistics

Gene_id	Symbol	Disease_read count	Normal_read count	Log₂FC	P-adj
ENSG00000107643	MAPK8	2141.92	980.48	1.1278	1.63E-36
ENSG00000108691	CCL2	965.58	14.1	6.0888	1.04E-31
ENSG00000169439	SDC2	726.54	12.05	5.9209	8.61E-31
ENSG00000160460	SPTBN4	100.36	16.26	2.626	3.57E-27
ENSG00000088899	LZTS3	436.07	138.93	1.6541	3.95E-24
ENSG00000095794	CREM	1760.64	355.27	2.3089	2.31E-23
ENSG00000144749	LRIG1	1648.48	755.18	1.127	2.46E-22
ENSG00000171793	CTPS1	1093.29	384.58	1.5064	1.08E-21
ENSG00000176641	RNF152	182.81	8.89	4.3723	5.64E-20
ENSG00000260196	-	163.81	50.63	1.6952	6.05E-19

Displayed as the top 10 genes with up-regulated expression.

Citation: Li F, Ren X, Liu JX, Wang TD, Wang B, Wei XB. Integrative transcriptomic and proteomic analysis reveals that SERPING1 inhibits neuronal proliferation via the CaMKII-CREB-BDNF pathway in schizophrenia. World J Psychiatry 2025; 15(2): 100214
URL: https://www.wjgnet.com/2220-3206/full/v15/i2/100214.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i2.100214