Copyright
©The Author(s) 2025.
World J Psychiatry. Jan 19, 2025; 15(1): 101186
Published online Jan 19, 2025. doi: 10.5498/wjp.v15.i1.101186
Published online Jan 19, 2025. doi: 10.5498/wjp.v15.i1.101186
No. | Metabolites | Retention time/minute | m/z | Formula | VIP | P value | Trend | Scan mode |
1 | Platelet-activating factor | 9.44 | 524.36951 | C26 H54 N O7 P | 2.09169 | 0.000 | ↓ | + |
2 | 2-amino-1,3,4-octadecanetriol | 6.441 | 318.29908 | C18 H39 N O3 | 1.88102 | 0.000 | ↑ | + |
3 | Palmitic acid | 6.402 | 274.27291 | C16 H32 O2 | 1.86839 | 0.000 | ↑ | + |
4 | Cortisol | 5.742 | 363.21555 | C21 H30 O5 | 1.91193 | 0.000 | ↑ | + |
5 | Stearic acid | 6.99 | 302.30423 | C18 H36 O2 | 1.59533 | 0.000 | ↑ | + |
6 | Hexadecanamide | 10.073 | 256.26277 | C16 H33 N O | 1.47424 | 0.000 | ↑ | + |
7 | Arachidic acid | 7.54 | 330.33567 | C20 H40 O2 | 1.17354 | 0.000 | ↑ | + |
8 | N-undecanoylglycine | 6.134 | 266.17185 | C13 H25 N O3 | 1.97952 | 0.000 | ↑ | + |
9 | Dihydrosphingosine 1-phosphate | 7.693 | 382.27068 | C18 H40 N O5 P | 1.37863 | 0.000 | ↑ | + |
10 | Palmitoyl ethanolamide | 9.734 | 300.28892 | C18 H37 N O2 | 1.70707 | 0.000 | ↑ | + |
11 | D-(+)-pyroglutamic acid | 1.01 | 130.04979 | C5 H7 N O3 | 1.21094 | 0.000 | ↓ | + |
12 | Oleoylethanolamide | 9.932 | 326.30444 | C20 H39 N O2 | 1.45824 | 0.000 | ↑ | + |
13 | D-erythro-sphingosine 1-phosphate | 7.519 | 380.25492 | C18 H38 N O5 P | 1.36048 | 0.000 | ↑ | + |
14 | Hypoxanthine | 1.111 | 137.04556 | C5 H4 N4 O | 1.33242 | 0.000 | ↓ | + |
15 | Glutamine | 0.96 | 147.07623 | C5 H10 N2 O3 | 1.24123 | 0.000 | ↑ | + |
16 | N-undecanoylglycine | 6.181 | 242.17601 | C13 H25 N O3 | 2.20108 | 0.000 | ↑ | - |
17 | L-glutamic acid | 0.893 | 146.0449 | C5 H9 N O4 | 1.9134 | 0.000 | ↓ | - |
18 | Sphingosine 1-phosphate | 7.587 | 378.24163 | C18 H38 N O5 P | 1.81005 | 0.000 | ↑ | - |
19 | N-phenylacetylglutamine | 4.125 | 263.10371 | C13 H16 N2 O4 | 1.68847 | 0.000 | ↑ | - |
20 | D-(-)-fructose | 0.853 | 179.05538 | C6 H12 O6 | 1.63729 | 0.000 | ↑ | - |
21 | 4-oxoproline | 0.968 | 128.03417 | C5 H7 N O3 | 1.54629 | 0.000 | ↓ | - |
22 | L-(+)-lactic acid | 1.093 | 89.02311 | C3 H6 O3 | 1.16621 | 0.000 | ↓ | - |
23 | Levothyroxine | 6.053 | 775.68055 | C15 H11 I4 N O4 | 1.51385 | 0.000 | ↑ | - |
24 | 3-hydroxybutyric acid | 1.784 | 103.03886 | C4 H8 O3 | 1.43635 | 0.000 | ↑ | - |
25 | Arachidonic acid | 10.197 | 303.23285 | C20 H32 O2 | 1.12287 | 0.000 | ↓ | - |
26 | Cis-5,8,11,14,17-eicosapentaenoic acid | 9.785 | 301.21728 | C20 H30 O2 | 1.09833 | 0.000 | ↓ | - |
- Citation: Song YN, Xia S, Sun Z, Chen YC, Jiao L, Wan WH, Zhang HW, Guo X, Guo H, Jia SF, Li XX, Cao SX, Fu LB, Liu MM, Zhou T, Zhang LF, Jia QQ. Metabolic pathway modulation by olanzapine: Multitarget approach for treating violent aggression in patients with schizophrenia. World J Psychiatry 2025; 15(1): 101186
- URL: https://www.wjgnet.com/2220-3206/full/v15/i1/101186.htm
- DOI: https://dx.doi.org/10.5498/wjp.v15.i1.101186