Shugan Jieyu capsule effects on peripheral blood micro-124, micro-132, and brain-derived neurotrophic factor in patients with mild to moderate depression

Table 6 Comparison of biochemical indicators between the two groups (mean ± SD, n = 30)

Group	Experimental	Control	t	P value
LDL-C (mmol/L)
Before treatment	3.21 ± 0.87	3.35 ± 0.68	0.694	0.490
After treatment	1.61 ± 0.66a	1.97 ± 0.63a	2.161	0.035
hs-CRP (mg/L)
Before treatment	8.47 ± 1.23	8.89 ± 1.56	1.157	0.252
After treatment	5.67 ± 0.59a	6.25 ± 0.67a	3.558	0.001
BDNF (ng/mL)
Before treatment	4.29 ± 0.97	4.58 ± 0.88	1.213	0.230
After treatment	13.71 ± 3.16a	10.43 ± 3.93a	3.563	0.001
miR-124
Before treatment	0.89 ± 0.25	0.93 ± 0.26	0.607	0.546
After treatment	1.22 ± 0.30a	1.01 ± 0.27a	2.850	0.006
miR-132
Before treatment	3.39 ± 0.78	3.22 ± 0.74	0.866	0.390
After treatment	1.41 ± 0.36a	1.73 ± 0.49a	2.883	0.006

^aP < 0.05, compared to before treatment within the same group.

LDL-C: Low-density lipoprotein cholesterol; hs-CRP: High-sensitivity C-reactive protein; BDNF: Brain-derived neurotrophic factor.