Predictive effect of lipopolysaccharide-stimulated inflammatory cytokines on symptoms of generalized anxiety disorder

Table 3 Inflammation-related cytokine levels after lipopolysaccharide stimulation

Inflammatory factor (normal range)	Control group (mean ± SD)	Generalized anxiety disorder group (mean ± SD)	t value	P value
IL-1β (0-12.4 pg/mL)	1592.06 ± 622.43	1538.99 ± 844.21	-0.440	0.660
IL-2 (0-5.71 pg/mL)	1.12 ± 0.67	1.13 ± 0.85	0.082	0.935
IL-4 (0-3 pg/mL)	1.44 ± 0.75	1.25 ± 0.77	-1.568	0.119
IL-5 (0-3.10 pg/mL)	1.09 ± 0.68	1.04 ± 0.39	-0.625	0.534
IL-6 (0-7 pg/mL)	14354.85 ± 1420.62	14657.66 ± 3347.42	0.173	0.443
IL-8 (0-20.60 pg/mL)	9515.79 ± 3803.61	11351.12 ± 6349.79	2.306	0.025
IL-10 (0-4.91 pg/mL)	1244.80 ± 2727.53	1049.45 ± 2877.97	-0.433	0.665
TNF-α (0-4.60 pg/mL)	2666.29 ± 1272.87	3197.81 ± 1887.78	1.676	0.045
IFN-γ (0-7.42 pg/mL)	34.72 ± 166.81	23.77 ± 74.81	-0.553	0.581
IL-17 (0-20.6 pg/mL)	26.91 ± 22.767	28.78 ± 30.53	0.426	0.671
IL-12p70 (0-3.4 pg/mL)	2.50 ± 2.84	1.94 ± 1.44	-1.633	0.104
IFN-α (0-8.5 pg/mL)	2.42 ± 2.24	2.01 ± 2.21	-1.181	0.240

IFN: Interferon; IL: Interleukin; TNF: Tumor necrosis factor.