Predictive effect of lipopolysaccharide-stimulated inflammatory cytokines on symptoms of generalized anxiety disorder

Table 2 Comparison of levels of inflammation-related cytokines between the two groups

Inflammatory factor (normal range)	Control group (mean ± SD)	Generalized anxiety disorder group (mean ± SD)	t value	P value
IL-1β (0-12.4 pg/mL)	1.69 ± 1.04	1.96 ± 2.21	1.024	0.308
IL-2 (0-5.71 pg/mL)	1.45 ± 0.98	1.78 ± 1.40	1.684	0.094
IL-4 (0-3 pg/mL)	1.68 ± 1.14	2.19 ± 1.82	2.040	0.043
IL-5 (0-3.10 pg/mL)	1.27 ± 0.58	2.18 ± 1.80	4.044	0.001
IL-6 (0-7 pg/mL)	5.03 ± 3.11	5.06 ± 3.98	-0.40	0.968
IL-8 (0-20.60 pg/mL)	30.59 ± 41.33	57.53 ± 230.29	1.081	0.336
IL-10 (0-4.91 pg/mL)	2.30 ± 0.82	3.66 ± 5.86	2.163	0.056
TNF-α (0-4.60 pg/mL)	2.05 ± 1.25	2.42 ± 2.67	1.069	0.287
IFN-γ (0-7.42 pg/mL)	1.77 ± 1.29	2.02 ± 1.59	1.056	0.292
IL-17A (0-20.6 pg/mL)	7.23 ± 4.84	4.27 ± 4.42	-3.749	0.001
IL-12p70 (0-3.4 pg/mL)	2.07 ± 1.40	2.55 ± 2.54	1.443	0.151
IFN-α (0-8.5 pg/mL)	1.80 ± 1.20	3.42 ± 10.42	1.460	0.148

IFN: Interferon; IL: Interleukin; TNF: Tumor necrosis factor.