Exploring the role of interleukin-6 receptor blockade in epilepsy and associated neuropsychiatric conditions through a mendelian randomization study

Figure 2 Correlation between genetically mediated inhibition of interleukin 6 signaling and the risk of epilepsy. A: Forest plot displaying mendelian randomization (MR) effect estimates and 95% confidence intervals (CI) for the genetic proxied blockade effect of interleukin (IL)-6 receptor (IL6R) on epilepsy; B: Forest plot displaying MR effect estimates and 95%CI for the genetic proxied blockade effect of IL6R on generalized epilepsy; C: Forest plot displaying MR effect estimates and 95%CI for the genetic proxied blockade effect of IL6R on focal epilepsy; D: Forest plot displaying MR effect estimates and 95%CI for the genetic proxied blockade effect of IL6R on juvenile absence epilepsy, childhood absence epilepsy, and juvenile myoclonic epilepsy. SNP: Single nucleotide polymorphism; OR: Odds ratio; CI: Confidence intervals.