Clinical study of chemotherapy-related cognitive impairment in patients with non-Hodgkin lymphoma

Table 2 Comparison of cytokine and psychological tests before and after chemotherapy

Parameter	BT group	AT group	t/Z value	P value
MMSE	27 (23.75–29)	27 (23.75–29)	-1.16	0.24
VFT	45.20 ± 15.62	42.30 ± 17.53	2.16	< 0.05
SDMT	24.5 (10.5–36)	22.5 (12–33)	0.69	0.49
CDT	8 (3.5–9.25)	7 (2.5–9)	-2.1	< 0.05
RM	13.5 (9–17)	15 (13–18)	-3.7	< 0.01
PM	12.63 ± 3.61	14.43 ± 4.32	-4.97	< 0.01
ECog-12	1.71 (1.25-2.08)	1.79 (1.42-2.08)	-2.84	< 0.01

Data are n (range) or mean ± standard deviation. AT: After treatment; BT: Before treatment; CDT: Clock Drawing Test; ECog-12: Abbreviated Daily Cognition Scale; PM: Prospective memory; RM: Retrospective memory; SDMT: Symbol Number Pattern Test; VFT: Verbal Fluency Test; MMSE: Brief Psychiatric Examination Scale (Mini-Mental State Examination).