Impact of early refined nursing program on prognosis of middle-aged and elderly patients with cognitive dysfunction combined with cerebral infarction

Table 4 Changes in growth factors, mean ± SD

Item	Time (wk)	Experimental group (n = 32)	Control group (n = 28)	Inter-group comparison (F/P value)	Time comparison (F/P value)	Inter-group time interactive comparison (F/P value)
BNDF (ng/mL)	0	4.85 ± 0.79	4.92 ± 0.83	19.330/< 0.001	146.100/< 0.001	9.113/< 0.001
	6	6.63 ± 1.05a,b	6.07 ± 0.86b
	12	8.77 ± 1.25a,b	7.28 ± 1.14b
TGF-β1 (ng/L)	0	15.42 ± 2.54	15.68 ± 2.99	19.080/< 0.001	92.220/< 0.001	8.759/< 0.001
	6	20.44 ± 3.12a,b	18.56 ± 3.08b
	12	25.71 ± 3.52a,b	21.13 ± 3.66b
GDNF (pg/mL)	0	288.61 ± 25.26	282.74 ± 24.18	40.080/< 0.001	157.200/< 0.001	6.016/0.003
	6	346.59 ± 25.84a,b	312.72 ± 26.38b
	12	392.27 ± 29.96a,b	355.06 ± 30.47b

^aP < 0.05 compared with control group.

^bP < 0.05 compared with 0 wk.