Association of serum interleukin-6 with negative symptoms in stable early-onset schizophrenia

Figure 1 Comparison of serum Log interleukin-6 Levels and the relationship with clinical symptoms in different subject groups. A: Serum log interleukin-6 (IL-6) concentrations in chronic early-onset schizophrenia (EOS) patients, chronic adult-onset schizophrenia patients, and healthy controls (HCs). Concentrations were significantly higher in schizophrenia groups than HCs but did not differ between schizophrenia groups; B: Correlation between serum log IL-6 concentration and total Positive and Negative Syndrome Scale (PANSS)-negative scores in the EOS patient group; C: Correlation between serum log IL-6 concentration and PANSS Avolition/Asociality subscore in the EOS patient group. IL-6: Interleukin-6; EOS: Early-onset schizophrenia; HC: Healthy control; PANSS: Positive and Negative Syndrome Scale; AOS: Adult-onset schizophrenia.