Brain protective effect of dexmedetomidine vs propofol for sedation during prolonged mechanical ventilation in non-brain injured patients

Table 4 Comparison of S100-β serum levels between the two groups

Time	Dexmedetomidine		Propofol		P value
	n	S100-β	n	S100-β
Day 0	52	0.12 (0.06-0.18)	63	0.14 (0.08-0.23)	0.4080
Day 1	52	2.12 (2.03-2.22)	63	3.02 (2.92-3.18)	< 0.001
Day 2	52	2.30 (2.18-2.48)	63	3.53 (3.32-3.85)	< 0.001
Day 3	52	2.88 (2.67-3.05)	63	3.62 (3.39-4.06)	< 0.001
Day 4	35	3.58 (3.36-3.85)	40	4.70 (4.35-4.97)	< 0.001
Day 5	22	4.46 (4.34-4.58)	28	4.98 (4.86-5.44)	< 0.001
Day 6	15	4.83 (4.68-5.03)	19	5.33 (4.98-5.65)	0.0026
Day 7	10	5.06 (4.81-5.32)	14	5.38 (5.19-5.67)	0.0562