Predictive value of nutritional status and serological indicators in elderly patients with mild cognitive impairment

Table 1 Difference of demographic information, dietary information and serological information between two groups

Variables	Total (n = 295)	NMCI group (n = 134)	MCI group (n = 161)	Statistic	P value
Demographic information
Age, mean ± SD	70.68 ± 8.47	68.33 ± 7.56	72.63 ± 8.71	t = -4.49	< 0.001
Sex, n (%)				χ² = 0.42	0.516
Male	137 (46.44)	65 (48.51)	72 (44.72)
Female	158 (53.56)	69 (51.49)	89 (55.28)
BMI, mean ± SD	22.57 ± 4.15	22.75 ± 3.78	22.43 ± 4.45	t = 0.65	0.514
Hypertension, n (%)				χ² = 4.47	0.035
No	211 (71.53)	104 (77.61)	107 (66.46)
Yes	84 (28.47)	30 (22.39)	54 (33.54)
Diabetes, n (%)				χ² = 10.18	0.001
No	228 (77.29)	115 (85.82)	113 (70.19)
Yes	67 (22.71)	19 (14.18)	48 (29.81)
Hyperlipemia, n (%)				χ² = 4.23	0.040
No	233 (78.98)	113 (84.33)	120 (74.53)
Yes	62 (21.02)	21 (15.67)	41 (25.47)
Cardiovascular disease, n (%)				χ² = 4.59	0.032
No	225 (76.27)	110 (82.09)	115 (71.43)
Yes	70 (23.73)	24 (17.91)	46 (28.57)
Pulmonary disease, n (%)				χ² = 0.35	0.554
No	256 (86.78)	118 (88.06)	138 (85.71)
Yes	39 (13.22)	16 (11.94)	23 (14.29)
Kidney disease, n (%)				χ² = 0.06	0.808
No	265 (89.83)	121 (90.30)	144 (89.44)
Yes	30 (10.17)	13 (9.70)	17 (10.56)
Dietary information
Smoking, n (%)				χ² = 7.10	0.008
No	178 (60.34)	92 (68.66)	86 (53.42)
Yes	117 (39.66)	42 (31.34)	75 (46.58)
Drinking, n (%)				χ² = 0.10	0.750
No	190 (64.41)	85 (63.43)	105 (65.22)
Yes	105 (35.59)	49 (36.57)	56 (34.78)
Tea, n (%)				χ² = 3.32	0.069
No	232 (78.64)	99 (73.88)	133 (82.61)
Yes	63 (21.36)	35 (26.12)	28 (17.39)
Coffee, n (%)				χ² = 4.55	0.033
No	250 (84.75)	107 (79.85)	143 (88.82)
Yes	45 (15.25)	27 (20.15)	18 (11.18)
Spicy diet, n (%)				χ² = 0.11	0.735
No	204 (69.15)	94 (70.15)	110 (68.32)
Yes	91 (30.85)	40 (29.85)	51 (31.68)
High-sweet diet, n (%)				χ² = 0.05	0.815
No	236 (80.00)	108 (80.60)	128 (79.50)
Yes	59 (20.00)	26 (19.40)	33 (20.50)
High fried diet, n (%)				χ² = 0.67	0.413
No	236 (80.00)	110 (82.09)	126 (78.26)
Yes	59 (20.00)	24 (17.91)	35 (21.74)
High-salt diet, n (%)				χ² = 7.42	0.006
No	203 (68.81)	103 (76.87)	100 (62.11)
Yes	92 (31.19)	31 (23.13)	61 (37.89)
High cholesterol diet, n (%)				χ² = 4.69	0.030
No	220 (74.58)	108 (80.60)	112 (69.57)
Yes	75 (25.42)	26 (19.40)	49 (30.43)
High-vitamin diet, n (%)				χ² = 5.62	0.018
No	176 (59.66)	70 (52.24)	106 (65.84)
Yes	119 (40.34)	64 (47.76)	55 (34.16)
Edible oil type, n (%)				χ² = 0.47	0.494
Vegetable oil	192 (65.08)	90 (67.16)	102 (63.35)
Animal oil	103 (34.92)	44 (32.84)	59 (36.65)
Serological indicators
RBC, mean ± SD	4.65 ± 1.02	4.83 ± 1.05	4.51 ± 0.96	t = 2.80	0.005
WBC, mean ± SD	7.17 ± 3.37	6.97 ± 3.45	7.33 ± 3.32	t = -0.91	0.362
NLR, mean ± SD	2.25 ± 0.61	2.02 ± 0.53	2.43 ± 0.61	t = -6.12	< 0.001
PLT, mean ± SD	168.71 ± 29.96	171.31 ± 31.69	166.54 ± 28.37	t = 1.36	0.174
IL-6 increases, n (%)				χ² = 2.18	0.140
No	219 (74.24)	105 (78.36)	114 (70.81)
Yes	76 (25.76)	29 (21.64)	47 (29.19)
TC, mean ± SD	5.01 ± 1.21	4.92 ± 1.17	5.10 ± 1.25	t = -1.27	0.204
TG, mean ± SD	1.29 ± 0.40	1.25 ± 0.36	1.32 ± 0.43	t = -1.31	0.191
HDL-C, mean ± SD	1.36 ± 0.25	1.41 ± 0.27	1.33 ± 0.21	t = 2.74	0.007
LDL-C, mean ± SD	3.29 ± 0.41	3.22 ± 0.31	3.35 ± 0.47	t = -2.96	0.003

NMCI: Non-mild cognitive impairment; MCI: Mild cognitive impairment; BMI: Body mass index; RBC: Red blood cell; WBC: White blood cell; NLR: Neutrophil lymphocyte ratio; PLT: Platelet; IL-6: Interleukin-6; TC: Total cholesterol; TG: Triglycerides; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol.