Interaction between serum inflammatory cytokines and brain-derived neurotrophic factor in cognitive function among first-episode schizophrenia patients

Table 3 Correlation analysis between Chinese brief cognitive test scores of various dimensions in the schizophrenia group and serum brain derived neurotrophic factor and inflammatory cytokines (n = 84)

Variable	Information processing speed		Attention		Working memory		Comprehensive + execution ability
	r value	P value	r value	P value	r value	P value	r value	P value
IL-1β	-0.198	0.071	-0.226a	0.039	-0.324a	0.003	-0.284a	0.009
IL-4	0.123	0.266	0.025	0.823	0.089	0.421	0.116	0.294
IL-6	-0.315a	0.004	-0.412b	< 0.001	-0.236a	0.030	-0.386b	< 0.001
IL-10	0.122	0.270	0.161	0.143	-0.025	0.822	0.105	0.343
BDNF	0.290a	0.008	0.189	0.085	0.296a	0.006	0.357b	< 0.001

^aP < 0.05.

^bP < 0.001.

BDNF: Brain derived neurotrophic factor; IL: Interleukin.